Kumari Divya, Bruyn Elise de, Al-Qawasmi Faisal
Department of Radiology, University of Chicago Medicine, Chicago, Illinois.
University of Illinois College of Medicine Peoria, Peoria, Illinois.
Semin Intervent Radiol. 2024 Aug 19;41(3):270-277. doi: 10.1055/s-0044-1788338. eCollection 2024 Jun.
Neuroendocrine tumors are an indolent, heterogeneous group of tumors that primarily arise from the gastropancreatic tract and lungs. Most patients present with liver metastases at the time of diagnosis, which cause significant morbidity and mortality due to excess hormone secretion, bile duct obstruction, and liver damage. A small percentage of these patients are eligible for potential cure through surgical resection. However, interventional radiology provides liver-directed therapies, such as percutaneous ablation, transarterial embolization, chemoembolization, and radioembolization, for palliative care and potential bridging to debulking and surgical resection of neuroendocrine liver metastases. This article aims to provide a brief overview of these liver-directed therapies focusing on the pre-, intra-, and postprocedural imaging findings.
神经内分泌肿瘤是一组生长缓慢、异质性的肿瘤,主要起源于胃肠道和肺部。大多数患者在诊断时已出现肝转移,由于激素分泌过多、胆管梗阻和肝损伤,导致显著的发病率和死亡率。这些患者中有一小部分有通过手术切除实现潜在治愈的可能。然而,介入放射学提供了针对肝脏的治疗方法,如经皮消融、经动脉栓塞、化疗栓塞和放射性栓塞,用于姑息治疗以及可能作为通向神经内分泌肝转移灶减瘤和手术切除的桥梁。本文旨在简要概述这些针对肝脏的治疗方法,并重点介绍术前、术中和术后的影像学表现。