Saritas Ahmet Gokhan, Gul Mehmet Onur, Ulku Abdullah, Gumus Serdar, Aydin Ishak, Akcam Atilgan Tolga
Department of General Surgery, Cukurova University Balcali Training and Research Hospital, Adana, Turkiye.
Department of Surgical Oncology, Malatya Training and Research Hospital, Malatya, Turkiye.
North Clin Istanb. 2024 Aug 5;11(4):328-335. doi: 10.14744/nci.2023.36776. eCollection 2024.
The present study reviews the records of patients with solid pseudopapillary pancreas neoplasm (SPT).
A total of 13 patients diagnosed with SPT were included in the study. The criteria for SPT in the pathology specimens were the presence of cells with an oval round orthochromatic nucleus, with a thin chromatin structure and no nucleolus distinction, lined around a fibrovascular papilla in cystic areas.
The study included 11 female and two male patients, with a mean age of 33.07 (range: 16-73) years. All operated patients underwent open surgery, with five undergoing a subtotal pancreatectomy and splenectomy; one a distal pancreatectomy and splenectomy; four a spleen-preserving distal pancreatectomy; and one a pancreaticoduodenectomy. None of the operated patients developed recurrence during the long-term follow-up. The mean follow-up time of operable patients was 69.18 (range: 22-97) months, and none had metastasis at follow-up. The mean follow-up time for the malignant SPT patients was 2.75 (1.5-4) months.
SPTs are rare pancreatic tumors encountered more frequently today due to advances in imaging methods and have a low potential of recurrence and a good prognosis.
本研究回顾实性假乳头状胰腺肿瘤(SPT)患者的记录。
本研究共纳入13例确诊为SPT的患者。病理标本中SPT的标准是在囊性区域有围绕纤维血管乳头排列的细胞,这些细胞具有椭圆形圆形的正染色质核,染色质结构薄且无核仁区分。
该研究包括11例女性患者和2例男性患者,平均年龄为33.07岁(范围:16 - 73岁)。所有接受手术的患者均接受了开放手术,其中5例行胰腺次全切除术和脾切除术;1例行胰体尾切除术和脾切除术;4例行保留脾脏的胰体尾切除术;1例行胰十二指肠切除术。所有接受手术的患者在长期随访中均未出现复发。可手术患者的平均随访时间为69.18个月(范围:22 - 97个月),随访时均无转移。恶性SPT患者的平均随访时间为2.75个月(1.5 - 4个月)。
SPT是一种罕见的胰腺肿瘤,由于成像方法的进步,如今更常遇到,其复发潜力低且预后良好。