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岩斜部脑膜瘤继发三叉神经痛的立体定向放射外科治疗后切除术(病例报告及文献复习)。

Posterior petrous meningioma with secondary trigeminal neuralgia: microsurgical resection after stereotactic radiosurgery (case report and literature review).

机构信息

Saint-Petersburg City Multi-field Hospital No. 2, St. Petersburg, Russia.

Mechnikov North-Western State Medical University, St. Petersburg, Russia.

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 2024;88(4):85-91. doi: 10.17116/neiro20248804185.

Abstract

According to the literature, cerebellopontine angle tumors cause secondary trigeminal neuralgia and other symptoms of neurovascular compression in 1-9.9% of cases. We present a 58-year-old patient with left-sided secondary trigeminal neuralgia caused by ipsilateral posterior petrous meningioma. Stereotactic irradiation was followed by effective tumor growth control. However, residual trigeminal pain paroxysms significantly reduced the quality of life and required subsequent microsurgery. Trigeminal facial pain regressed after total resection of tumor. Considering this clinical case, we would like to discuss several issues: follow-up of meningioma requiring radiosurgery, course of secondary trigeminal neuralgia in a patient with apical petrous meningioma, characteristics of pain before and after radiosurgery, the best treatment option for these patients. Stereotactic radiosurgery seems unreasonable for CPA tumors with secondary trigeminal neuralgia. Indeed, persistent pain is possible even after tumor shrinkage. Moreover, primary stereotactic irradiation significantly complicates subsequent resection of tumor.

摘要

据文献报道,1-9.9%的小脑脑桥角肿瘤可引起继发性三叉神经痛和其他颅神经血管压迫症状。我们报告了一例 58 岁左侧继发性三叉神经痛患者,由同侧岩后脑膜瘤引起。立体定向放疗后肿瘤生长得到有效控制。然而,残留的三叉神经痛发作明显降低了生活质量,需要后续的显微手术。肿瘤全切后,三叉神经面部疼痛消退。考虑到这个临床病例,我们想讨论几个问题:需要放射外科治疗的脑膜瘤的随访、岩骨尖脑膜瘤患者继发性三叉神经痛的病程、放射外科前后疼痛的特征、这些患者的最佳治疗选择。对于伴有继发性三叉神经痛的 CPA 肿瘤,立体定向放射外科似乎不合理。事实上,即使肿瘤缩小,仍有可能持续疼痛。此外,原发性立体定向照射显著增加了肿瘤后续切除的难度。

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