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一名女性患者胫骨多微生物性骨髓炎——病例报告

in polymicrobial osteomyelitis of the tibia in a female patient - a case report.

作者信息

Ioannou Petros, Maraki Sofia, Velivasakis Emmanuel, Kofteridis Diamantis P

机构信息

MD, MSc, PhD, Internal Medicine Department, University Hospital of Heraklion, Heraklion, PC 71110, Greece, and School of Medicine, University of Crete, Heraklion, PC 71003, Greece.

MD, PhD, Microbiology Department, University Hospital of Heraklion, Heraklion, PC 71110, Greece.

出版信息

Germs. 2024 Mar 31;14(1):95-100. doi: 10.18683/germs.2024.1421. eCollection 2024 Mar.

Abstract

INTRODUCTION

(formerly ) is a microorganism rarely reported as a cause of infection. It is a Gram-positive, non-motile, and non-spore-forming bacterium belonging to the Micrococcaceae family. It is known for its environmental ubiquity, being frequently found in soil, water, and other ecological niches.

CASE REPORT

A 39-year-old woman with a history of glucose-6-phosphate dehydrogenase deficiency and multiple surgeries at the left lower extremity for osteomyelitis at the left tibia presented with a relapse of chronic osteomyelitis of the left tibia. She underwent surgical debridement, and cultures grew , and , according to identification with matrix-assisted laser desorption/ionization-time of flight mass spectrometry. Targeted antimicrobial treatment with ciprofloxacin and amoxicillin-clavulanate for six weeks led to patient recovery.

CONCLUSIONS

Accurate identification by advanced diagnostic techniques is essential for effectively managing rare pathogens. Further research and reporting of cases are needed to understand better the epidemiology, pathogenesis, optimal treatment, and improved clinical outcomes associated with infections.

摘要

引言

(以前称为 )是一种很少被报道为感染病因的微生物。它是一种革兰氏阳性、无运动性且不形成芽孢的细菌,属于微球菌科。它以在环境中广泛存在而闻名,经常在土壤、水和其他生态位中被发现。

病例报告

一名39岁女性,有葡萄糖-6-磷酸脱氢酶缺乏病史,因左胫骨骨髓炎在左下肢进行了多次手术,现出现左胫骨慢性骨髓炎复发。她接受了手术清创,根据基质辅助激光解吸/电离飞行时间质谱鉴定,培养物中生长出 以及 。用环丙沙星和阿莫西林-克拉维酸进行六周的靶向抗菌治疗使患者康复。

结论

先进诊断技术的准确鉴定对于有效管理罕见病原体至关重要。需要进一步的研究和病例报告,以更好地了解与 感染相关的流行病学、发病机制、最佳治疗方法以及改善临床结果。

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