Yi Seah Xin, Tham Xiang Cong, Aloweni Fazila, Kua Sandra Mei Yu, Tham Wei Ying, Lim Siew Hoon
Division of Radiological Sciences, Singapore General Hospital, Singapore.
SingHealth Community Hospitals, Singapore.
Heliyon. 2024 Jul 30;10(15):e35450. doi: 10.1016/j.heliyon.2024.e35450. eCollection 2024 Aug 15.
Hyperthyroidism and thyroid cancer significantly impact health, and often require Radioactive Iodine (RAI) therapy. Anxiety is common in patients undergoing RAI, particularly related to dietary compliance. This study aimed to assess the effectiveness of the mobile health application, DietLens in reducing anxiety and increasing satisfaction in patients preparing for RAI therapy, focusing on low-iodine diet (LID). A quasi-experimental study was conducted in a Singapore tertiary hospital outpatient department from March 13, 2019 to March 27, 2020, involving patients scheduled for their first RAI treatment. Participants were divided into a control group receiving standard care and an intervention group using DietLens alongside standard care. Anxiety levels were assessed using the Zung Self-Rating Anxiety Scale, and satisfaction levels were measured through self-reported questionnaires. In the study, 56 participants were initially divided into control (n = 28) and intervention (n = 28) groups. After accounting for dropouts, 50 participants finished the study, with each group comprising 25 individuals. Anxiety levels were similar between groups pre-intervention. Post-intervention, the intervention group displayed a significant decrease in anxiety levels compared to the control group (independent -test: t (48) = 2.50, p = 0.02). The multivariate linear regression analysis indicated that being in the intervention group was significantly associated with a decrease in post-intervention anxiety score (β = -4.03, 95 % CI: -7.33 to -0.72, p = 0.02). Fisher's Exact Test revealed a borderline significant difference in satisfaction with educational materials and the overall treatment process, with 100 % of the intervention group expressing satisfaction compared to 80 % in the control group, resulting in a p-value of 0.052 in both instances. DietLens was effective in reducing anxiety and enhancing satisfaction related to RAI therapy preparation, particularly in managing a LID, highlighting a beneficial role for digital interventions in healthcare settings.
甲状腺功能亢进症和甲状腺癌对健康有重大影响，通常需要进行放射性碘（RAI）治疗。焦虑在接受RAI治疗的患者中很常见，尤其是与饮食依从性相关。本研究旨在评估移动健康应用程序DietLens在降低准备接受RAI治疗患者的焦虑水平和提高满意度方面的有效性，重点关注低碘饮食（LID）。2019年3月13日至2020年3月27日，在新加坡一家三级医院门诊部进行了一项准实验研究，纳入计划接受首次RAI治疗的患者。参与者被分为接受标准护理的对照组和在标准护理基础上使用DietLens的干预组。使用zung自评焦虑量表评估焦虑水平，并通过自我报告问卷测量满意度。在该研究中，56名参与者最初被分为对照组（n = 28）和干预组（n = 28）。在考虑退出者后，50名参与者完成了研究，每组各有25人。干预前两组的焦虑水平相似。干预后，与对照组相比，干预组的焦虑水平显著降低（独立样本t检验：t(48)=2.50，p = 0.02）。多元线性回归分析表明，处于干预组与干预后焦虑评分降低显著相关（β = -4.03，95%置信区间：-7.33至-0.72，p = 0.02）。Fisher精确检验显示，在对教育材料和总体治疗过程的满意度方面存在临界显著差异，干预组100%表示满意，而对照组为80%，在这两种情况下p值均为0.052。DietLens在降低与RAI治疗准备相关的焦虑和提高满意度方面有效，尤其是在管理低碘饮食方面，突出了数字干预在医疗环境中的有益作用。
