Ahmadi Alireza, Sabri Mohammad Reza, Ghaderian Mehdi, Ramezani Nezhad Davood, Dehghan Bahar, Mahdavi Chehreh, Sedighi Mohsen
Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Trauma and Injury Research Center, Iran University of Medical Sciences, Tehran, Iran.
ARYA Atheroscler. 2024 Mar-Apr;20(2):41-49. doi: 10.48305/arya.2023.41893.2906.
Balloon Pulmonary Valvuloplasty (BPV) is a procedure for Pulmonary Stenosis (PS) treatment. In this study, right ventricle (RV) performance was determined through 2D-Speckle Tracking Echocardiography (2D-STE).
The study involved 25 diagnosed children with PS undergoing BPV and 25 normal children. They were examined using 2D-STE and Linear Mixed Model (LMM) approach was used to determine changes in Pulmonary Valve Peak Gradient (PVPG), Tricuspid Annular Plane Systolic Excursion (TAPSE), strain and Strain Rate (SR) for RV, and Ejection Fraction for Left Ventricle (LVEF).
Notable differences were found between two groups in TAPSE (), global strain (), apical septal strain (), middle septal strain (), basal septal strain (), apical lateral SR (), middle lateral SR (), basal lateral SR (), and apical septal SR (). Post-BPV, there was an increase in LVEF () and TAPSE () but PVPG decreased (). Following BPV, an increase was observed in apical lateral strain (), middle septal strain (), apical septal strain (), middle septal strain (), basal septal strain (), apical septal SR (), and middle septal SR (). Gender was remarkably correlated with mean changes in basal lateral strain (), middle septal strain (), and middle septal SR (). Age of PS children was related to mean change in basal septal strain () and basal septal SR ().
Strain and SR in RV improved post-BPV in children with PS. The gender and age of the children revealed remarkable effects on RV strain and SR changes after BPV.
球囊肺动脉瓣成形术（BPV）是一种治疗肺动脉狭窄（PS）的手术。在本研究中，通过二维斑点追踪超声心动图（2D-STE）测定右心室（RV）功能。
该研究纳入了25例确诊为PS并接受BPV的儿童以及25例正常儿童。使用2D-STE对他们进行检查，并采用线性混合模型（LMM）方法来确定肺动脉瓣峰值梯度（PVPG）、三尖瓣环平面收缩期位移（TAPSE）、RV应变和应变率（SR）以及左心室射血分数（LVEF）的变化。
两组在TAPSE（）、整体应变（）、心尖间隔应变（）、中间间隔应变（）、基底间隔应变（）、心尖外侧SR（）、中间外侧SR（）、基底外侧SR（）和心尖间隔SR（）方面存在显著差异。BPV术后，LVEF（）和TAPSE（）增加，但PVPG降低（）。BPV术后，心尖外侧应变（）、中间间隔应变（）、心尖间隔应变（）、中间间隔应变（）、基底间隔应变（）、心尖间隔SR（）和中间间隔SR（）增加。性别与基底外侧应变（）、中间间隔应变（）和中间间隔SR（）的平均变化显著相关。PS儿童的年龄与基底间隔应变（）和基底间隔SR（）的平均变化有关。
PS患儿BPV术后RV的应变和SR有所改善。儿童的性别和年龄对BPV术后RV应变和SR的变化有显著影响。
