• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

健康对照者运动性言语功能神经影像学的特征及可重复性。

The characteristics and reproducibility of motor speech functional neuroimaging in healthy controls.

作者信息

Kenyon Katherine H, Boonstra Frederique, Noffs Gustavo, Morgan Angela T, Vogel Adam P, Kolbe Scott, Van Der Walt Anneke

机构信息

Department of Neuroscience, School of Translational Medicine, Melbourne, VIC, Australia.

Redenlab Inc., Melbourne, VIC, Australia.

出版信息

Front Hum Neurosci. 2024 Aug 7;18:1382102. doi: 10.3389/fnhum.2024.1382102. eCollection 2024.

DOI:10.3389/fnhum.2024.1382102
PMID:39171097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11335534/
Abstract

INTRODUCTION

Functional magnetic resonance imaging (fMRI) can improve our understanding of neural processes subserving motor speech function. Yet its reproducibility remains unclear. This study aimed to evaluate the reproducibility of fMRI using a word repetition task across two time points.

METHODS

Imaging data from 14 healthy controls were analysed using a multi-level general linear model.

RESULTS

Significant activation was observed during the task in the right hemispheric cerebellar lobules IV-V, right putamen, and bilateral sensorimotor cortices. Activation between timepoints was found to be moderately reproducible across time in the cerebellum but not in other brain regions.

DISCUSSION

Preliminary findings highlight the involvement of the cerebellum and connected cerebral regions during a motor speech task. More work is needed to determine the degree of reproducibility of speech fMRI before this could be used as a reliable marker of changes in brain activity.

摘要

引言

功能磁共振成像（fMRI）能够增进我们对支持运动性言语功能的神经过程的理解。然而，其可重复性仍不明确。本研究旨在评估使用单词重复任务在两个时间点进行fMRI的可重复性。

方法

使用多级一般线性模型分析了14名健康对照者的成像数据。

结果

在任务期间，右侧半球小脑小叶IV - V、右侧壳核以及双侧感觉运动皮层观察到显著激活。发现时间点之间的激活在小脑中随时间具有中度可重复性，但在其他脑区则不然。

讨论

初步研究结果突出了小脑和相连脑区在运动性言语任务中的参与。在将言语fMRI用作脑活动变化的可靠标志物之前，需要开展更多工作来确定其可重复性程度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab16/11335534/b2d8f3246c1c/fnhum-18-1382102-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab16/11335534/7b4e717c4daa/fnhum-18-1382102-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab16/11335534/1f478fa2d902/fnhum-18-1382102-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab16/11335534/3beb5b930394/fnhum-18-1382102-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab16/11335534/b2d8f3246c1c/fnhum-18-1382102-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab16/11335534/7b4e717c4daa/fnhum-18-1382102-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab16/11335534/1f478fa2d902/fnhum-18-1382102-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab16/11335534/3beb5b930394/fnhum-18-1382102-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab16/11335534/b2d8f3246c1c/fnhum-18-1382102-g004.jpg

相似文献

1
The characteristics and reproducibility of motor speech functional neuroimaging in healthy controls.健康对照者运动性言语功能神经影像学的特征及可重复性。
Front Hum Neurosci. 2024 Aug 7;18:1382102. doi: 10.3389/fnhum.2024.1382102. eCollection 2024.
2
fMRI reveals two distinct cerebral networks subserving speech motor control.功能磁共振成像揭示了两个不同的大脑网络，它们负责言语运动控制。
Neurology. 2005 Feb 22;64(4):700-6. doi: 10.1212/01.WNL.0000152156.90779.89.
3
Cerebellar tDCS Modulates Neural Circuits during Semantic Prediction: A Combined tDCS-fMRI Study.小脑经颅直流电刺激在语义预测过程中调节神经回路：一项经颅直流电刺激与功能磁共振成像联合研究
J Neurosci. 2017 Feb 8;37(6):1604-1613. doi: 10.1523/JNEUROSCI.2818-16.2017. Epub 2017 Jan 9.
4
Functional topography of the cerebellum for motor and cognitive tasks: an fMRI study.小脑在运动和认知任务中的功能拓扑：一项 fMRI 研究。
Neuroimage. 2012 Jan 16;59(2):1560-70. doi: 10.1016/j.neuroimage.2011.08.065. Epub 2011 Aug 31.
5
The Effect of Speech Repetition Rate on Neural Activation in Healthy Adults: Implications for Treatment of Aphasia and Other Fluency Disorders.言语重复率对健康成年人神经激活的影响：对失语症及其他流利性障碍治疗的启示
Front Hum Neurosci. 2018 Feb 27;12:69. doi: 10.3389/fnhum.2018.00069. eCollection 2018.
6
A functional MRI study of motor dysfunction in Friedreich's ataxia.弗里德里希共济失调症运动功能障碍的功能磁共振成像研究。
Brain Res. 2012 Aug 30;1471:138-54. doi: 10.1016/j.brainres.2012.06.035. Epub 2012 Jul 3.
7
An fMRI study of intra-individual functional topography in the human cerebellum.一项关于人类小脑内个体功能拓扑的 fMRI 研究。
Behav Neurol. 2010;23(1-2):65-79. doi: 10.3233/BEN-2010-0268.
8
Within-session and between-session reproducibility of cerebral sensorimotor activation: a test--retest effect evidenced with functional magnetic resonance imaging.大脑感觉运动激活的组内和组间可重复性：功能磁共振成像证实的重测效应
J Cereb Blood Flow Metab. 2001 May;21(5):592-607. doi: 10.1097/00004647-200105000-00014.
9
Functional magnetic resonance imaging of human brain activity in a verbal fluency task.在言语流畅性任务中对人类大脑活动进行的功能磁共振成像。
J Neurol Neurosurg Psychiatry. 1998 Apr;64(4):492-8. doi: 10.1136/jnnp.64.4.492.
10
Parietal operculum and motor cortex activities predict motor recovery in moderate to severe stroke.顶叶岛盖和运动皮层活动可预测中重度中风后的运动恢复。
Neuroimage Clin. 2017 Jan 26;14:518-529. doi: 10.1016/j.nicl.2017.01.023. eCollection 2017.

本文引用的文献

1
A New Functional Magnetic Resonance Imaging Localizer for Preoperative Language Mapping Using a Sentence Completion Task: Validity, Choice of Baseline Condition, and Test-Retest Reliability.一种使用句子完成任务进行术前语言映射的新型功能磁共振成像定位器：有效性、基线条件的选择以及重测信度
Front Hum Neurosci. 2022 Mar 30;16:791577. doi: 10.3389/fnhum.2022.791577. eCollection 2022.
2
How the motor system copes with aging: a quantitative meta-analysis of the effect of aging on motor function control.运动系统如何应对衰老：衰老对运动功能控制影响的定量元分析。
Commun Biol. 2022 Jan 20;5(1):79. doi: 10.1038/s42003-022-03027-2.
3
Speech as a Biomarker for Depression.
言语作为抑郁症的生物标志物。
CNS Neurol Disord Drug Targets. 2023;22(2):152-160. doi: 10.2174/1871527320666211213125847.
4
Brain changes underlying progression of speech motor programming impairment.言语运动编程障碍进展背后的大脑变化。
Brain Commun. 2021 Sep 2;3(3):fcab205. doi: 10.1093/braincomms/fcab205. eCollection 2021.
5
Assessment of speech and fine motor coordination in children with autism spectrum disorder.自闭症谱系障碍儿童的言语和精细运动协调评估。
IEEE Access. 2020;8:127535-127545. doi: 10.1109/ACCESS.2020.3007348. Epub 2020 Jul 10.
6
Functional MRI Can Be Highly Reliable, but It Depends on What You Measure: A Commentary on Elliott et al. (2020).功能磁共振成像可以高度可靠，但这取决于你所测量的内容：对埃利奥特等人（2020年）的评论
Psychol Sci. 2021 Apr;32(4):622-626. doi: 10.1177/0956797621989730. Epub 2021 Mar 8.
7
Syllabic Diadochokinesis in Adults With and Without Traumatic Brain Injury: Severity, Stability, and Speech Considerations.有和没有创伤性脑损伤的成年人的音节交替运动速率：严重程度、稳定性及言语考量
Am J Speech Lang Pathol. 2021 Jun 18;30(3S):1400-1409. doi: 10.1044/2020_AJSLP-20-00158. Epub 2021 Feb 25.
8
A guide to the measurement and interpretation of fMRI test-retest reliability.功能磁共振成像（fMRI）重测信度的测量与解读指南
Curr Opin Behav Sci. 2021 Aug;40:27-32. doi: 10.1016/j.cobeha.2020.12.012. Epub 2021 Jan 20.
9
Emerging behavioral and neuroimaging biomarkers for early and accurate characterization of autism spectrum disorders: a systematic review.用于自闭症谱系障碍早期准确特征描述的新兴行为和神经影像生物标志物：一项系统综述
Transl Psychiatry. 2021 Jan 13;11(1):42. doi: 10.1038/s41398-020-01178-6.
10
Reliability of single-subject neural activation patterns in speech production tasks.言语产生任务中单试次神经激活模式的可靠性。
Brain Lang. 2021 Jan;212:104881. doi: 10.1016/j.bandl.2020.104881. Epub 2020 Dec 2.