Rohla Miklos, Philip Legate, Wolf Janina, Jaffer Farouc A, Räber Lorenz
Department of Cardiology, Bern University Hospital, Inselspital, University of Bern, Freiburgstrasse 20, 3010 Bern, Switzerland.
Institute of Pathology, University of Bern, Bern, Switzerland.
Eur Heart J Case Rep. 2024 Aug 9;8(8):ytae420. doi: 10.1093/ehjcr/ytae420. eCollection 2024 Aug.
ST-elevation myocardial infarction (STEMI) is a cardiac emergency that requires prompt diagnosis and treatment. We describe a challenging and complex case of managing acute STEMI in a patient with severe anaemia, deranged clotting profile, and infective prodrome.
A 54-year-old Caucasian gentleman was referred by his general practitioner as an emergency after presenting with acute onset of chest pain. His electrocardiogram revealed anterior ST elevation. His past medical history includes a mechanical aortic valve, requiring anticoagulation, and a recent gastrointestinal bleed secondary to type C gastritis. His initial presentation was further complicated by severe anaemia, deranged clotting profile, and elevated infective markers. He required a prompt transfer to the catheterization laboratory to assess and stabilize the situation. We discuss the emerging challenges during treatment, particularly as the diagnosis of septic embolism from infective prosthetic valve endocarditis was unfolding, requiring urgent cardiac surgery.
Acute coronary vessel closure leading to STEMI from septic embolism secondary to prosthetic aortic valve endocarditis is very rare. It is essential to consider the whole picture of the presentation for timely diagnosis and tailored treatment.
ST段抬高型心肌梗死(STEMI)是一种需要迅速诊断和治疗的心脏急症。我们描述了一例在患有严重贫血、凝血指标异常和感染前驱症状的患者中管理急性STEMI的具有挑战性和复杂性的病例。
一名54岁的白种男性在出现急性胸痛后被其全科医生作为急症转诊。他的心电图显示前壁ST段抬高。他既往有机械主动脉瓣病史,需要抗凝治疗,近期因C型胃炎继发胃肠道出血。他最初的表现因严重贫血、凝血指标异常和感染指标升高而进一步复杂化。他需要迅速转至导管室以评估和稳定病情。我们讨论了治疗过程中出现的新挑战,尤其是在感染性人工瓣膜心内膜炎导致的脓毒性栓塞诊断逐渐明确时,这需要紧急心脏手术。
人工主动脉瓣心内膜炎继发脓毒性栓塞导致急性冠状动脉闭塞进而引起STEMI非常罕见。全面考虑临床表现对于及时诊断和针对性治疗至关重要。