Ahmad Ahmad Fayez
From the Oral and Maxillofacial Surgery Department, Tishreen Hospital, Lattakia, Syria.
Plast Reconstr Surg Glob Open. 2024 Aug 21;12(8):e6088. doi: 10.1097/GOX.0000000000006088. eCollection 2024 Aug.
The clinical manifestations of mucormycosis vary depending on the location of the infection. In general, sepsis begins within the oral cavity or nose and then spreads to the central nervous system through the eyes. It is typically seen in immunocompromised patients, including those who have been exposed to high doses of cortisone, such as corona virus disease 2019 patients. The infection can lead to severe destruction of the bones of the palate, nose, and maxillary and sinusoid areas. Treatment may require both medical and surgical intervention. In the secondary stage of recovery from mucormycosis, various methods of reconstructive surgery for the external nasal structure can be used. To my knowledge, this is the first case that compares to secondary nasal restoration. A former patient with mucormycosis was treated using an autologous bone graft from the ilium, and after 2 years, the restoration was done using a silicone implant due to the absorption of the bone graft. The restoration using the silicone implant led to satisfactory results for the patient and the surgeon from an aesthetic standpoint, and we did not notice any inflammatory or infectious symptoms during the 11-month follow-up period.
毛霉菌病的临床表现因感染部位而异。一般来说，败血症始于口腔或鼻腔，然后通过眼睛扩散到中枢神经系统。它通常见于免疫功能低下的患者，包括那些接触过高剂量可的松的患者，如2019冠状病毒病患者。感染可导致腭骨、鼻骨以及上颌和鼻窦区域的严重破坏。治疗可能需要药物和手术干预。在毛霉菌病恢复的第二阶段，可以采用各种外鼻结构重建手术方法。据我所知，这是第一例进行二次鼻修复比较的病例。一名曾患毛霉菌病的患者使用来自髂骨的自体骨移植进行治疗，2年后，由于骨移植吸收，使用硅胶植入物进行修复。从美学角度来看，使用硅胶植入物进行修复对患者和外科医生都产生了令人满意的效果，并且在11个月的随访期内我们未发现任何炎症或感染症状。
