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一例老年女性原发性干燥综合征继发视神经脊髓炎谱系障碍罕见病例报告。

A Rare Case of Neuromyelitis Optica Spectrum Disorder Secondary to Primary Sjögren's Syndrome in an Older Woman.

机构信息

Department of Internal Medicine, Faculty of Medicine, Balikesir University, Balikesir, Turkey.

Department of Geriatric Medicine, Faculty of Medicine, Balikesir University, Balikesir, Turkey.

出版信息

Prague Med Rep. 2024;125(3):232-238. doi: 10.14712/23362936.2024.21.

Abstract

Primary Sjögren's syndrome is an autoimmune disorder that is characterized by lymphocytic infiltration of salivary and lacrimal glands. The extra-glandular manifestations might be arthritis, myalgia, glomerulonephritis, skin rashes, and neurologic involvement. One of the uncommon neurologic manifestations is neuromyelitis optica spectrum disorder (NMOSD). In the present case, an older woman is reported that was diagnosed with NMOSD secondary to keratoconjunctivitis sicca, which is rare in geriatric practice.

摘要

原发性干燥综合征是一种自身免疫性疾病,其特征是唾液腺和泪腺的淋巴细胞浸润。腺外表现可能包括关节炎、肌痛、肾小球肾炎、皮疹和神经受累。神经病变的一种不常见表现是视神经脊髓炎谱系疾病(NMOSD)。在本病例中,报告了一位老年女性,因干燥性角膜结膜炎继发 NMOSD 而被诊断,这种情况在老年医学实践中较为罕见。

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