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术前识别需要术后全胃肠外营养支持的外科癌症患者。

Preoperative identification of the surgical cancer patient in need of postoperative supportive total parenteral nutrition.

作者信息

Meguid M M, Meguid V

出版信息

Cancer. 1985 Jan 1;55(1 Suppl):258-62. doi: 10.1002/1097-0142(19850101)55:1+<258::aid-cncr2820551309>3.0.co;2-h.

Abstract

In the absence of specific therapy, nutrition was the mainstay of medicine in ancient times. Because of the current emphasis on modern treatment modalities in the fight against cancer, the provision of adequate nutrition is frequently overlooked. Because of the inconsistent results obtained from randomized trials of total parenteral nutrition (TPN) in cancer patients undergoing chemotherapy and radiation therapy, ambivalence about the usefulness of TPN as an adjunct to cancer therapy (particularly as it pertains to surgical patients) is further confused by the lack of appropriate criteria for the use of TPN postoperatively. The incidence of malnutrition in relation to certain cancer types is high. Malnutrition is associated with a higher incidence of both postoperative complications and mortality when compared to the well nourished patient. Consequently, preoperative criteria were developed to identify that group of cancer patients requiring abdominal operation who are at high risk and in whom planned nutritional support should be initiated postoperatively. Use of these criteria provides a rational basis for the use of TPN postoperatively.

摘要

在缺乏特效疗法的情况下,营养在古代是医学的支柱。由于当前在抗癌斗争中强调现代治疗方式,充足营养的供给常常被忽视。由于在接受化疗和放疗的癌症患者中进行的全胃肠外营养(TPN)随机试验结果不一致,且术后使用TPN缺乏适当标准,使得对于TPN作为癌症治疗辅助手段(尤其是对手术患者而言)的效用存在矛盾观点,这进一步加剧了困惑。与某些癌症类型相关的营养不良发生率很高。与营养良好的患者相比,营养不良与术后并发症和死亡率的较高发生率相关。因此,制定了术前标准,以识别那些需要接受腹部手术且风险高、计划术后开始营养支持的癌症患者群体。使用这些标准为术后使用TPN提供了合理依据。

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