Chen Qiaoyan
Foundation Department, Zhe Jiang Tong Ji Vocational College of Science and Technology, Hangzhou, Zhejiang 311231, China.
Exp Gerontol. 2024 Oct 15;196:112550. doi: 10.1016/j.exger.2024.112550. Epub 2024 Sep 2.
Aging is an unavoidable process marked by numerous physiological and psychological changes that profoundly impact overall health and quality of life. As the global population ages, there is a growing interest in non-pharmacological therapies that can mitigate the adverse effects of aging and promote longevity. This narrative review explores the broad spectrum of non-pharmacological mechanisms offering anti-aging benefits, with a special emphasis on holistic practices such as yoga, meditation, and lifestyle interventions. These therapies influence critical biological processes, including reducing oxidative stress, modulating chronic inflammation, enhancing immune function, and preserving telomere length-key markers of cellular aging. Additionally, these practices contribute to improved cardiovascular health, musculoskeletal strength, and mental well-being, fostering a comprehensive approach to healthy aging. Yoga, for instance, combines physical postures, breath control, and meditation to enhance physical flexibility, mental clarity, and emotional balance. Meditation practices are shown to reduce stress and improve cognitive function, further supporting healthy aging. Lifestyle modifications, such as diet and regular physical activity, complement these therapies by promoting overall vitality and reducing the risk of age-related diseases. This review underscores the potential of integrating these non-pharmacological strategies into daily routines to enhance resilience against aging, improve quality of life, and extend healthspan. Furthermore, it highlights the need for continued research to fully elucidate the mechanisms by which these therapies exert their anti-aging effects and to develop evidence-based guidelines for their implementation.
衰老是一个不可避免的过程,其特征是众多生理和心理变化,这些变化深刻影响着整体健康和生活质量。随着全球人口老龄化,人们对非药物疗法的兴趣日益浓厚,这些疗法可以减轻衰老的不利影响并促进长寿。这篇叙述性综述探讨了具有抗衰老益处的广泛非药物机制,特别强调了瑜伽、冥想和生活方式干预等整体疗法。这些疗法影响关键的生物学过程,包括减少氧化应激、调节慢性炎症、增强免疫功能以及保持端粒长度——细胞衰老的关键标志。此外,这些疗法有助于改善心血管健康、肌肉骨骼力量和心理健康,促进一种全面的健康衰老方法。例如,瑜伽将身体姿势、呼吸控制和冥想结合起来,以增强身体柔韧性、思维清晰度和情绪平衡。冥想练习被证明可以减轻压力并改善认知功能,进一步支持健康衰老。生活方式的改变,如饮食和定期体育活动,通过促进整体活力和降低与年龄相关疾病的风险来补充这些疗法。这篇综述强调了将这些非药物策略融入日常生活以增强抗衰能力、提高生活质量和延长健康寿命的潜力。此外,它强调了持续研究的必要性,以充分阐明这些疗法发挥抗衰老作用的机制,并制定基于证据的实施指南。