使用具有笛卡尔欠采样和压缩感知的VIBE序列对头颈部区域进行动态对比增强磁共振成像。

Dynamic contrast enhanced MRI of the head and neck region using a VIBE sequence with Cartesian undersampling and compressed sensing.

作者信息

Kubicka F, Nitschke L, Penzkofer T, Tan Q, Nickel M D, Wakonig K M, Fahlenkamp U L, Lerchbaumer M, Michallek F, Dommerich S, Hamm B, Wagner M, Walter-Rittel T

机构信息

Department of Radiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

Department of Radiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; Berlin Institute of Health, Berlin, Germany.

出版信息

Magn Reson Imaging. 2024 Nov;113:110220. doi: 10.1016/j.mri.2024.110220. Epub 2024 Aug 22.

DOI:10.1016/j.mri.2024.110220

PMID:39173963

Abstract

OBJECTIVES

Compressed sensing allows for image reconstruction from sparsely sampled k-space data, which is particularly useful in dynamic contrast enhanced MRI (DCE-MRI). The aim of the study was to assess the diagnostic value of a volume-interpolated 3D T1-weighted spoiled gradient-echo sequence with variable density Cartesian undersampling and compressed sensing (CS) for head and neck MRI.

METHODS

Seventy-one patients with clinical indications for head and neck MRI were included in this study. DCE-MRI was performed at 3 Tesla magnet using CS-VIBE (variable density undersampling, temporal resolution 3.4 s, slice thickness 1 mm). Image quality was compared to standard Cartesian VIBE. Three experienced readers independently evaluated image quality and lesion conspicuity on a 5-point Likert scale and determined the DCE-derived time intensity curve (TIC) types.

RESULTS

CS-VIBE demonstrated higher image quality scores compared to standard VIBE with respect to overall image quality (4.3 ± 0.6 vs. 4.2 ± 0.7, p = 0.682), vessel contour (4.6 ± 0.4 vs. 4.4 ± 0.6, p < 0.001), muscle contour (4.4 ± 0.5 vs. 4.5 ± 0.6, p = 0.302), lesion conspicuity (4.5 ± 0.7 vs. 4.3 ± 0.9, p = 0.024) and showed improved fat saturation (4.8 ± 0.3 vs. 3.8 ± 0.4, p < 0.001) and movement artifacts were significantly reduced (4.6 ± 0.6 vs. 3.7 ± 0.7, p < 0.001). Standard VIBE outperformed CS-VIBE in the delineation of pharyngeal mucosa (4.2 ± 0.5 vs. 4.6 ± 0.6, p < 0.001). Lesion size in cases where a focal lesion was identified was similar for all readers for CS-VIBE and standard VIBE (p = 0.101). TIC curve assessment showed good interobserver agreement (k=0.717).

CONCLUSION

CS-VIBE with variable density Cartesian undersampling allows for DCE-MRI of the head and neck region with diagnostic, high image quality and high temporal resolution.

摘要

目的

压缩感知允许从稀疏采样的 k 空间数据进行图像重建，这在动态对比增强磁共振成像（DCE-MRI）中特别有用。本研究的目的是评估具有可变密度笛卡尔欠采样和压缩感知（CS）的容积内插三维 T1 加权扰相梯度回波序列用于头颈部 MRI 的诊断价值。

方法

本研究纳入了 71 例有头颈部 MRI 临床指征的患者。在 3 特斯拉磁体上使用 CS-VIBE（可变密度欠采样，时间分辨率 3.4 秒，层厚 1 毫米）进行 DCE-MRI。将图像质量与标准笛卡尔 VIBE 进行比较。三位经验丰富的阅片者独立地在 5 点李克特量表上评估图像质量和病变清晰度，并确定 DCE 衍生的时间-强度曲线（TIC）类型。

结果

与标准 VIBE 相比，CS-VIBE 在整体图像质量（4.3±0.6 对 4.2±0.7，p = 0.682）、血管轮廓（4.6±0.4 对 4.4±0.6，p < 0.001）、肌肉轮廓（4.4±0.5 对 4.5±0.6，p = 0.302）、病变清晰度（4.5±0.7 对 4.3±0.9，p = 0.024）方面显示出更高的图像质量评分，并且脂肪抑制改善（4.8±0.3 对 3.8±0.4，p < 0.001），运动伪影显著减少（4.6±0.6 对 3.7±0.7，p < 0.001）。在咽黏膜的描绘方面，标准 VIBE 优于 CS-VIBE（4.2±0.5 对 4.6±0.6，p < 0.001）。对于 CS-VIBE 和标准 VIBE，所有阅片者在识别出局灶性病变的病例中病变大小相似（p = 0.101）。TIC 曲线评估显示观察者间一致性良好（k = 0.717）。