Suppr超能文献

轴承的选择对55岁及以上骨关节炎患者全髋关节置换术的植入物生存率有影响:来自北欧关节置换登记协会2005年至2017年的158,044例患者的结果。

Choice of Bearings Influences the Implant Survival of Total Hip Arthroplasty in Patients Who Have Osteoarthritis Aged 55 Years or Older: Results of 158,044 Patients From the Nordic Arthroplasty Register Association From 2005 to 2017.

作者信息

Pakarinen Oskari, Ponkilainen Ville, Varnum Claus, Pedersen Alma B, Overgaard Søren, Kärrholm Johan, Rolfson Ola, Fenstad Anne Marie, Furnes Ove, Hallan Geir, Mäkelä Keijo, Eskelinen Antti

机构信息

Department of Surgery, Päijät-Häme Central Hospital, Lahti, Finland.

Department of Surgery, Central Finland Hospital Nova, Jyväskylä, Finland.

出版信息

J Arthroplasty. 2025 Feb;40(2):437-442.e2. doi: 10.1016/j.arth.2024.08.015. Epub 2024 Aug 20.

Abstract

BACKGROUND

The aim of our study was to compare implant survival rates of different total hip arthroplasty (THA) bearings in the Nordic Arthroplasty Register Association.

METHODS

All conventional primary THAs performed between 2005 and 2017 in patients aged more than 55 years who had primary osteoarthritis were studied. Metal-on-highly cross-linked polyethylene (MoXLP), ceramic-on-highly cross-linked polyethylene (CoXLP), ceramic-on-ceramic (CoC), and metal-on-metal (MoM) bearings were included. The outcome was a revision. Kaplan-Meier (KM) estimates were calculated at 5 and 10 years. The risk for revision was analyzed using a flexible parametric survival model adjusted for nation, age, sex, femoral head size, and femoral fixation.

RESULTS

A total of 158,044 THAs were included. The 5-year KM estimates were 95.9% (95% confidence interval [CI] 95.8 to 96.1) in MoXLP, 95.8% (95% CI 95.6 to 96.1) in CoXLP, 96.7% (95% CI 96.4 to 97.0) in CoC, and 93.9% (95% CI 93.5 to 94.4) in MoM. The 10-years KM estimates were 94.2% (94.0 to 94.5) in MoXLP, 94.3% (93.9 to 94.8) in CoXLP, 95.4% (95.0 to 95.9) in CoC, and 85.5% (84.9 to 86.2) in MoM. Compared with MoXLP, the adjusted risk for revision was lower in CoC (hazard ratio [HR] 0.6, CI 0.5 to 0.6), similar in CoXLP (HR 1.0, CI 0.9 to 1.0), and higher in MoM (HR 1.3, CI 1.2 to 1.4).

CONCLUSIONS

We found that MoXLP, CoXLP, and CoC bearings evinced comparably high implant survival rates up to 10 years, and they can all be regarded as safe options in this patient group. The MoM bearings were associated with clearly lower survivorship. The CoC bearings had the highest implant survival and a lower adjusted risk for revision compared with highly cross-linked polyethylene bearings.

摘要

背景

我们研究的目的是比较北欧关节置换登记协会中不同全髋关节置换术(THA)轴承的植入物生存率。

方法

对2005年至2017年间为年龄超过55岁的原发性骨关节炎患者进行的所有传统初次THA进行研究。纳入金属对高交联聚乙烯(MoXLP)、陶瓷对高交联聚乙烯(CoXLP)、陶瓷对陶瓷(CoC)和金属对金属(MoM)轴承。结局指标为翻修。计算5年和10年的Kaplan-Meier(KM)估计值。使用根据国家、年龄、性别、股骨头大小和股骨固定情况调整的灵活参数生存模型分析翻修风险。

结果

共纳入158,044例THA。MoXLP的5年KM估计值为95.9%(95%置信区间[CI]95.8至96.1),CoXLP为95.8%(95%CI 95.6至96.1),CoC为96.7%(95%CI 96.4至97.0),MoM为93.9%(95%CI 93.5至94.4)。MoXLP的10年KM估计值为94.2%(94.0至94.5),CoXLP为94.3%(93.9至94.8),CoC为95.4%(95.0至95.9),MoM为85.5%(84.9至86.2)。与MoXLP相比,CoC的调整后翻修风险较低(风险比[HR]0.6,CI 0.5至0.6),CoXLP相似(HR 1.0,CI 0.9至1.0),MoM较高(HR 1.3,CI 1.2至1.4)。

结论

我们发现,MoXLP、CoXLP和CoC轴承在长达10年的时间里显示出相当高的植入物生存率,在该患者群体中它们都可被视为安全选择。MoM轴承的生存率明显较低。与高交联聚乙烯轴承相比,CoC轴承的植入物生存率最高且调整后翻修风险较低。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验