Wang Xi, Chen Xingming, Niu Yanyan, Huo Hong, Zhu Xiaoli
Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Department of Otorhinolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
J Voice. 2024 Aug 21. doi: 10.1016/j.jvoice.2024.07.036.
Schwannomas originating within the larynx are rare and there is no clear consensus on the diagnostic workup or treatment. This study aims to explore the clinical features of laryngeal schwannoma and evaluate the surgical method of transoral endoscopic excision, especially with coblation.
Data from patients diagnosed with laryngeal schwannoma who underwent surgery at Peking Union Medical College Hospital from 2017 to 2022 were retrospectively analyzed. All cases were evaluated with a flexible laryngoscope and computed tomography and/or magnetic resonance imaging before surgery.
Four patients, comprising one male and three females aged 19 to 61years, were included. All patients presented with persistent and progressive hoarseness, and two also experienced dyspnea on exertion. One patient was a recurrent case who underwent transoral tumor resection with a laser, while another patient had received a transoral incisional biopsy before visiting our hospital. Transoral excision was performed in each case. One tumor was excised using microlaryngeal instruments under a microscope, and the other three with coblation assisted by an operating laryngoscope. All laryngeal schwannomas were removed in a single block. All patients were successfully extubated following surgery, recovered without complications, and showed no evidence of recurrence.
Transoral surgery better preserves laryngeal function, reduces complications, and shortens hospital stays. Transoral endoscopic excision, particularly when performed with coblation, is highly recommended for its excellent visualization and ability to completely excise the tumor. This method is a safe and effective approach, especially for large laryngeal schwannomas in hard-to-reach locations.
起源于喉部的神经鞘瘤较为罕见,对于其诊断检查或治疗尚无明确的共识。本研究旨在探讨喉神经鞘瘤的临床特征,并评估经口内镜切除手术方法,尤其是使用低温等离子消融术。
回顾性分析2017年至2022年在北京协和医院接受手术治疗的喉神经鞘瘤患者的数据。所有病例在手术前均使用纤维喉镜以及计算机断层扫描和/或磁共振成像进行评估。
纳入4例患者,包括1例男性和3例女性,年龄在19至61岁之间。所有患者均表现为持续性进行性声音嘶哑,2例患者还伴有活动时呼吸困难。1例患者为复发病例,曾接受激光经口肿瘤切除术,另1例患者在来我院就诊前接受过经口切开活检。每例均行经口切除术。1例肿瘤在显微镜下使用显微喉器械切除,另外3例在手术喉镜辅助下使用低温等离子消融术切除。所有喉神经鞘瘤均完整切除。所有患者术后均成功拔管,恢复过程无并发症,且无复发迹象。
经口手术能更好地保留喉功能,减少并发症并缩短住院时间。强烈推荐经口内镜切除,尤其是使用低温等离子消融术,因其具有良好的视野及完全切除肿瘤的能力。该方法是一种安全有效的方法,尤其适用于难以触及部位的大型喉神经鞘瘤。