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Pilot study of humanized glypican-3-targeted zirconium-89 immuno-positron emission tomography for hepatocellular carcinoma.

作者信息

Dickerson Lindsay K, Lehnert Adrienne L, Hamlin Donald K, Labadie Kevin P, Goodsell Kristin E, Liu Yongjun, Li Yawen, Wilbur D Scott, Miyaoka Robert, Park James O

机构信息

Department of Surgery, University of Washington, 1959 NE Pacific St., Box 356410, Seattle, WA, 98195, USA.

Department of Radiology, University of Washington, Seattle, WA, USA.

出版信息

EJNMMI Res. 2024 Aug 22;14(1):74. doi: 10.1186/s13550-024-01134-1.

DOI:10.1186/s13550-024-01134-1
PMID:39174756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11341507/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d258/11341507/6613d209ee42/13550_2024_1134_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d258/11341507/93e14c4be610/13550_2024_1134_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d258/11341507/fb57f7a40563/13550_2024_1134_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d258/11341507/de7eedf7b1b4/13550_2024_1134_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d258/11341507/6613d209ee42/13550_2024_1134_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d258/11341507/93e14c4be610/13550_2024_1134_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d258/11341507/fb57f7a40563/13550_2024_1134_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d258/11341507/de7eedf7b1b4/13550_2024_1134_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d258/11341507/6613d209ee42/13550_2024_1134_Fig4_HTML.jpg

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本文引用的文献

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J Nucl Med. 2024 Apr 1;65(4):586-592. doi: 10.2967/jnumed.123.266766.
2
Glypican-3 targeted positron emission tomography detects sub-centimeter tumors in a xenograft model of hepatocellular carcinoma.磷脂酰肌醇蛋白聚糖-3靶向正电子发射断层扫描在肝细胞癌异种移植模型中检测出亚厘米级肿瘤。
EJNMMI Res. 2023 Apr 27;13(1):35. doi: 10.1186/s13550-023-00980-9.
3
Site-Specifically Conjugated Single-Domain Antibody Successfully Identifies Glypican-3-Expressing Liver Cancer by Immuno-PET.
免疫 PET 成功鉴定了糖蛋白 3 表达肝癌的位点特异性偶联单域抗体。
J Nucl Med. 2023 Jul;64(7):1017-1023. doi: 10.2967/jnumed.122.265171. Epub 2023 Mar 30.
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Imaging ligands targeting glypican-3 receptor expression in hepatocellular carcinoma.靶向肝细胞癌中磷脂酰肌醇蛋白聚糖-3受体表达的成像配体。
Am J Nucl Med Mol Imaging. 2022 Aug 20;12(4):113-121. eCollection 2022.
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GPC3-targeted immunoPET imaging of hepatocellular carcinomas.GPC3 靶向免疫 PET 显像用于肝细胞癌。
Eur J Nucl Med Mol Imaging. 2022 Jul;49(8):2682-2692. doi: 10.1007/s00259-022-05723-x. Epub 2022 Feb 11.
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J Nucl Med. 2022 Jul;63(7):1033-1038. doi: 10.2967/jnumed.121.262562. Epub 2021 Nov 12.
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