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[预防老年认知能力下降:选定的一级预防方法]

[Prevention of cognitive decline in old age : Selected primary preventive approaches].

作者信息

Steinmetz Carolin, Schnieder Marlena, Heinemann Stephanie, Linke Anne, von Arnim Christine A F

机构信息

Klink für Geriatrie, Universitätsmedizin Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Deutschland.

Klinik für Neurologie, Universitätsmedizin Göttingen, Göttingen, Deutschland.

出版信息

Z Gerontol Geriatr. 2024 Oct;57(6):442-446. doi: 10.1007/s00391-024-02337-w. Epub 2024 Aug 22.

DOI:10.1007/s00391-024-02337-w
PMID:39174823
Abstract

There are currently 1.8 million people in Germany affected by dementia. Despite advances in research and new treatments, there is no cure for most cases of dementia. The evidence regarding the prevention of cognitive decline in old age is unclear. In addition to the optimized adjustment of drug treatment (e.g., arterial hypertension and diabetes mellitus), preventive measures that can be influenced by individuals themselves play an important role. These include areas such as physical and cognitive activity, remedying hearing loss, sleep, social contacts, abstaining from alcohol as well as tobacco consumption and nutrition. Multimodal concepts and digital approaches appear to be promising and an increase in evidence is expected in the coming years.

摘要

目前,德国有180万人受痴呆症影响。尽管研究取得进展且有了新的治疗方法,但大多数痴呆症病例仍无法治愈。关于预防老年人认知能力下降的证据尚不明确。除了优化药物治疗(如动脉高血压和糖尿病)外,个人自身能够影响的预防措施也起着重要作用。这些措施包括身体和认知活动、纠正听力损失、睡眠、社交、戒酒以及戒烟和营养等方面。多模式概念和数字方法似乎很有前景,预计未来几年证据将会增加。

相似文献

1
[Prevention of cognitive decline in old age : Selected primary preventive approaches].[预防老年认知能力下降:选定的一级预防方法]
Z Gerontol Geriatr. 2024 Oct;57(6):442-446. doi: 10.1007/s00391-024-02337-w. Epub 2024 Aug 22.
2
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Multi-domain interventions for the prevention of dementia and cognitive decline.多领域干预措施预防痴呆和认知能力下降。
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The Black Book of Psychotropic Dosing and Monitoring.《精神药物剂量与监测黑皮书》
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NIH Consensus Statement on Management of Hepatitis C: 2002.美国国立卫生研究院关于丙型肝炎管理的共识声明:2002年。
NIH Consens State Sci Statements. 2002;19(3):1-46.
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Antihypertensive withdrawal for the prevention of cognitive decline.停用抗高血压药物以预防认知功能减退。
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本文引用的文献

1
Diabetes, antidiabetic medications and risk of dementia: A systematic umbrella review and meta-analysis.糖尿病、抗糖尿病药物与痴呆风险:系统伞式评价和荟萃分析。
Diabetes Obes Metab. 2024 Feb;26(2):441-462. doi: 10.1111/dom.15331. Epub 2023 Oct 23.
2
A multidomain intervention against cognitive decline in an at-risk-population in Germany: Results from the cluster-randomized AgeWell.de trial.一项针对德国高危人群认知能力下降的多领域干预措施:来自 AgeWell.de 试验的集群随机对照结果。
Alzheimers Dement. 2024 Jan;20(1):615-628. doi: 10.1002/alz.13486. Epub 2023 Sep 28.
3
Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial.
美国针对听力损失老年人群认知能力下降的听力干预与健康教育培训对照研究(ACHIEVE):一项多中心随机对照试验
Lancet. 2023 Sep 2;402(10404):786-797. doi: 10.1016/S0140-6736(23)01406-X. Epub 2023 Jul 18.
4
Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons.MIND 饮食预防老年人认知能力下降的试验。
N Engl J Med. 2023 Aug 17;389(7):602-611. doi: 10.1056/NEJMoa2302368. Epub 2023 Jul 18.
5
Lecanemab in Early Alzheimer's Disease.早期阿尔茨海默病中的lecanemab
N Engl J Med. 2023 Jan 5;388(1):9-21. doi: 10.1056/NEJMoa2212948. Epub 2022 Nov 29.
6
Association of Catheter Ablation and Reduced Incidence of Dementia among Patients with Atrial Fibrillation during Long-Term Follow-Up: A Systematic Review and Meta-Analysis of Observational Studies.导管消融与心房颤动患者长期随访期间痴呆发病率降低的关联:一项观察性研究的系统评价和荟萃分析
J Cardiovasc Dev Dis. 2022 Apr 30;9(5):140. doi: 10.3390/jcdd9050140.
7
Associations of Multidomain Interventions With Improvements in Cognition in Mild Cognitive Impairment: A Systematic Review and Meta-analysis.多领域干预与轻度认知障碍认知改善的关联:系统评价和荟萃分析。
JAMA Netw Open. 2022 May 2;5(5):e226744. doi: 10.1001/jamanetworkopen.2022.6744.
8
Dementia prevention, intervention, and care: 2020 report of the Lancet Commission.《痴呆症的预防、干预与照护:柳叶刀委员会2020年报告》
Lancet. 2020 Aug 8;396(10248):413-446. doi: 10.1016/S0140-6736(20)30367-6. Epub 2020 Jul 30.
9
Evidence-based prevention of Alzheimer's disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials.基于证据的阿尔茨海默病预防:243 项观察性前瞻性研究和 153 项随机对照试验的系统评价和荟萃分析。
J Neurol Neurosurg Psychiatry. 2020 Nov;91(11):1201-1209. doi: 10.1136/jnnp-2019-321913. Epub 2020 Jul 20.
10
Investigation of antihypertensive class, dementia, and cognitive decline: A meta-analysis.抗高血压药物种类、痴呆与认知能力下降的关系:一项荟萃分析。
Neurology. 2020 Jan 21;94(3):e267-e281. doi: 10.1212/WNL.0000000000008732. Epub 2019 Dec 11.