Ichiki Junya, Yamasaki Koji, Zako Ryusei, Wada Takeshi, Kitagawa Kanta, Hirano Takaki, Kugimiya Aiko, Inoue Shuhei, Yamamoto Kotaro, Usui Ryosuke, Kinoshita Mitsuhiro, Yamamoto Masayoshi, Kondo Hiroshi
Department of Radiology, Teikyo University School of Medicine, Japan.
Department of Neurosurgery, Tsurumi Neurosurgery, Japan.
Interv Radiol (Higashimatsuyama). 2024 May 14;9(2):62-68. doi: 10.22575/interventionalradiology.2023-0014. eCollection 2024 Jul 1.
This retrospective study of patients with pulmonary arteriovenous malformations aims to assess the efficacy of embolization distal to the origin of the last normal branch of the pulmonary artery.
A total of 30 consecutive patients with 38 untreated pulmonary arteriovenous malformations underwent coil embolization distal to the origin of the last normal branch of the pulmonary artery between September 2015 and October 2021. The median (interquartile range) age of patients (5 males, 25 females) was 59 years (50-68 years old), and the median (interquartile range) sizes of the feeding artery and sac were 2.9 mm (2.3-3.8 mm) and 6.7 mm (5.4-9.7 mm), respectively. The technical success rate, persistence rate, and treatment-related complications were evaluated. Technical success was defined as the inability to identify the draining vein on feeding arteriography after coil embolization. Persistence was assessed using time-resolved magnetic resonance angiography.
Coil embolization was successful in all patients (100%). There was no persistence during a median (interquartile range) follow-up period of 23 months (10-45 months) for the 38 pulmonary arteriovenous malformations embolized with coils. No major complications were reported. Only minor complications following embolization occurred in 4 of 36 sessions, including local pain in 2 sessions (6%) and hemosputum in 2 sessions (6%).
Embolization distal to the origin of the last normal branch of the pulmonary artery is effective in preventing the persistence of pulmonary arteriovenous malformations.
本项对肺动静脉畸形患者的回顾性研究旨在评估在肺动脉最后一支正常分支起点远端进行栓塞的疗效。
2015年9月至2021年10月期间,共有30例连续患者的38处未经治疗的肺动静脉畸形在肺动脉最后一支正常分支起点远端接受了弹簧圈栓塞。患者(5例男性,25例女性)的年龄中位数(四分位间距)为59岁(50 - 68岁),供血动脉和瘤囊的大小中位数(四分位间距)分别为2.9毫米(2.3 - 3.8毫米)和6.7毫米(5.4 - 9.7毫米)。评估了技术成功率、留存率和治疗相关并发症。技术成功定义为弹簧圈栓塞后在供血动脉造影上无法识别引流静脉。使用时间分辨磁共振血管造影评估留存情况。
所有患者(100%)的弹簧圈栓塞均成功。在对38处用弹簧圈栓塞的肺动静脉畸形进行的中位数(四分位间距)为23个月(10 - 45个月)的随访期间,无留存情况。未报告重大并发症。在36次操作中,仅4次出现栓塞后轻微并发症,包括2次(6%)局部疼痛和2次(6%)咯血。
在肺动脉最后一支正常分支起点远端进行栓塞可有效防止肺动静脉畸形留存。