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The validity of serum ferritin levels in predicting cardiovascular events of metabolic dysfunction-associated steatotic liver disease patients may need more consideration.血清铁蛋白水平在预测代谢功能障碍相关脂肪性肝病患者心血管事件方面的有效性可能需要更多的考量。
Hepatobiliary Surg Nutr. 2024 Aug 1;13(4):755-756. doi: 10.21037/hbsn-24-217. Epub 2024 Jul 22.
2
Serum ferritin levels can predict long-term outcomes in patients with metabolic dysfunction-associated steatotic liver disease.血清铁蛋白水平可预测代谢功能障碍相关脂肪性肝病患者的长期预后。
Gut. 2024 Apr 5;73(5):825-834. doi: 10.1136/gutjnl-2023-330815.
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Associations between serum ferritin baselines and trajectories and the incidence of metabolic dysfunction-associated steatotic liver disease: a prospective cohort study.血清铁蛋白基线和轨迹与代谢功能障碍相关脂肪性肝病发病的关系：一项前瞻性队列研究。
Lipids Health Dis. 2024 May 17;23(1):141. doi: 10.1186/s12944-024-02129-6.
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Systemic impacts of metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) on heart, muscle, and kidney related diseases.代谢功能障碍相关脂肪性肝病（MASLD）和代谢功能障碍相关脂肪性肝炎（MASH）对心脏、肌肉和肾脏相关疾病的全身影响。
Front Cell Dev Biol. 2024 Jul 16;12:1433857. doi: 10.3389/fcell.2024.1433857. eCollection 2024.
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Non-invasive Scores and Serum Biomarkers for Fatty Liver in the Era of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD): A Comprehensive Review From NAFLD to MAFLD and MASLD.代谢相关脂肪性肝病时代非侵入性评分和血清生物标志物在脂肪性肝病中的应用：从非酒精性脂肪性肝病到代谢相关脂肪性肝病和脂肪性肝病的综合评价。
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Cardiovascular outcomes post bariatric surgery in patients with metabolic dysfunction-associated steatotic liver disease - A systematic review and meta-analysis.代谢功能障碍相关脂肪性肝病患者减肥手术后的心血管结局——一项系统评价和荟萃分析
Clin Res Hepatol Gastroenterol. 2024 Jan;48(1):102261. doi: 10.1016/j.clinre.2023.102261. Epub 2023 Dec 7.
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Metabolic dysfunction-associated steatotic liver disease and risk of cardiovascular disease.代谢相关脂肪性肝病与心血管疾病风险。
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Association of Metabolic Dysfunction-Associated Steatotic Liver Disease/Non-alcoholic Fatty Liver Disease With Type 2 Diabetes Mellitus: A Case-Control Study in a Tertiary Care Hospital in Pakistan.代谢功能障碍相关脂肪性肝病/非酒精性脂肪性肝病与2型糖尿病的关联：巴基斯坦一家三级医疗医院的病例对照研究
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Cognitive dysfunction in early experimental metabolic dysfunction-associated steatotic liver disease is associated with systemic inflammation and neuroinflammation.早期实验性代谢功能障碍相关脂肪性肝病中的认知功能障碍与全身炎症和神经炎症有关。
JHEP Rep. 2023 Dec 21;6(3):100992. doi: 10.1016/j.jhepr.2023.100992. eCollection 2024 Mar.
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Prognostic value of metabolic dysfunction-associated steatotic liver disease over coronary computed tomography angiography findings: comparison with no-alcoholic fatty liver disease.代谢相关脂肪性肝病与冠状动脉 CT 血管造影结果的预后价值比较：与非酒精性脂肪肝的比较。
Cardiovasc Diabetol. 2024 May 10;23(1):167. doi: 10.1186/s12933-024-02268-1.

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1
Prevalence and Prognostic Value of the Novel Consensus Definition of Metabolic Hyperferritinemia in Patients With Heart Failure With Preserved Ejection Fraction Across Different Glucose Metabolism States.
J Am Heart Assoc. 2025 Jul;14(13):e040100. doi: 10.1161/JAHA.124.040100. Epub 2025 Jun 18.

本文引用的文献

1
Serum ferritin levels can predict long-term outcomes in patients with metabolic dysfunction-associated steatotic liver disease.血清铁蛋白水平可预测代谢功能障碍相关脂肪性肝病患者的长期预后。
Gut. 2024 Apr 5;73(5):825-834. doi: 10.1136/gutjnl-2023-330815.
2
A Population-Based and Clinical Cohort Validation of the Novel Consensus Definition of Metabolic Hyperferritinemia.基于人群的和临床队列验证新型代谢性高血铁定义的共识。
J Clin Endocrinol Metab. 2024 May 17;109(6):1540-1549. doi: 10.1210/clinem/dgad749.
3
Associations between metabolic hyperferritinaemia, fibrosis-promoting alleles and clinical outcomes in steatotic liver disease.代谢性铁过载、纤维化促进等位基因与脂肪性肝病临床结局的相关性。
Liver Int. 2024 Feb;44(2):389-398. doi: 10.1111/liv.15787. Epub 2023 Nov 16.
4
Association of gestational hypertriglyceridemia, diabetes with serum ferritin levels in early pregnancy: a retrospective cohort study.早孕期妊娠性高甘油三酯血症、糖尿病与血清铁蛋白水平的相关性：一项回顾性队列研究。
Front Endocrinol (Lausanne). 2023 Jul 19;14:1067655. doi: 10.3389/fendo.2023.1067655. eCollection 2023.
5
Consensus Statement on the definition and classification of metabolic hyperferritinaemia.代谢性铁蛋白血症定义和分类的共识声明。
Nat Rev Endocrinol. 2023 May;19(5):299-310. doi: 10.1038/s41574-023-00807-6. Epub 2023 Feb 17.
6
Relation between Serum Ferritin Level and the Risk of Acute Myocardial Infarction.血清铁蛋白水平与急性心肌梗死风险的关系。
J Assoc Physicians India. 2022 Aug;70(8):11-12. doi: 10.5005/japi-11001-0059.
7
Combined Associations of Serum Ferritin and Body Size Phenotypes With Cardiovascular Risk Profiles: A Chinese Population-Based Study.血清铁蛋白与体型表型联合与心血管风险特征的关系：一项基于中国人群的研究。
Front Public Health. 2021 Feb 15;9:550011. doi: 10.3389/fpubh.2021.550011. eCollection 2021.
8
Performance and comparability of laboratory methods for measuring ferritin concentrations in human serum or plasma: A systematic review and meta-analysis.用于测量人血清或血浆中铁蛋白浓度的实验室方法的性能和可比性：系统评价和荟萃分析。
PLoS One. 2018 May 3;13(5):e0196576. doi: 10.1371/journal.pone.0196576. eCollection 2018.
9
Comparison of four immunoassays to measure serum ferritin concentrations and iron deficiency prevalence among non-pregnant Cambodian women and Congolese children.四种免疫测定法用于测量柬埔寨非孕女性和刚果儿童血清铁蛋白浓度及缺铁患病率的比较。
Clin Chem Lab Med. 2017 Jan 1;55(1):65-72. doi: 10.1515/cclm-2016-0421.
10
The statin-iron nexus: anti-inflammatory intervention for arterial disease prevention.他汀类药物与铁的关联：动脉疾病预防的抗炎干预。
Am J Public Health. 2013 Apr;103(4):e105-12. doi: 10.2105/AJPH.2012.301163. Epub 2013 Feb 14.

The validity of serum ferritin levels in predicting cardiovascular events of metabolic dysfunction-associated steatotic liver disease patients may need more consideration.

作者信息

Yang Jie, Liu Qing, Li Jie, Sun Chao

机构信息

Department of Gastroenterology, Tianjin Medical University General Hospital Airport Hospital, Tianjin, China.

Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin, China.

出版信息

Hepatobiliary Surg Nutr. 2024 Aug 1;13(4):755-756. doi: 10.21037/hbsn-24-217. Epub 2024 Jul 22.

DOI:10.21037/hbsn-24-217
PMID:39175730
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11336545/
Abstract
摘要