Yassari Fatemeh, Marashian Seyed Mehran, Ghasemi Monfared Abolfazl, Lookzadeh Somayeh
Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Tanaffos. 2023 Apr;22(4):426-432.
The current study tried to assess the effects of CKD on the severity and outcome of COPD in a population of patients who referred to our tertiary center in Tehran through a 3-year time section.
Through a retrospective cross-sectional design, the current study tried to assess the effects of chronic kidney disease (CKD) on the health situation and some spirometric and para-clinical parameters as well as their outcomes in patients who had been hospitalized for COPD. The participants had already COPD and we separate them into two groups with or without CKD.
Regarding the outcome of hospitalizations, 94% of the COPD and 77.9% of the COPD+CKD group were discharged in good health condition while 6% and 22.1% deceased, respectively. This shows significantly higher death rate in the latter group and the findings obtained the odds ratio of 4.5 for CKD to raise this rate.
The current study could suggest an absolute relationship between CKD and COPD in terms of respiratory and blood parameters as well as the mutual effects of the diseases on the outcome of each.
本研究试图通过一个为期3年的时间段，评估慢性肾脏病（CKD）对转诊至德黑兰我们的三级中心的患者群体中慢性阻塞性肺疾病（COPD）严重程度和预后的影响。
通过回顾性横断面设计，本研究试图评估慢性肾脏病（CKD）对因COPD住院患者的健康状况、一些肺功能和辅助临床参数及其预后的影响。参与者已患有COPD，我们将他们分为有或无CKD的两组。
关于住院结局，94%的COPD患者和77.9%的COPD+CKD组患者健康出院，而分别有6%和22.1%的患者死亡。这表明后一组的死亡率显著更高，研究结果得出CKD使该死亡率升高的优势比为4.5。
本研究表明，在呼吸和血液参数方面，CKD与COPD之间存在绝对关联，以及这两种疾病对彼此预后的相互影响。
