Integrated Perspectives on Clinical Decision Support: A Comparative Analysis of Knowledge Management Approaches.

We analyze five approaches to knowledge management in clinical decision support (CDS) systems: pattern recognition based on annotated imaging data, mining of stored structured medical data, text mining of published texts, computable knowledge design, and general or specific text corpora for large language models. Each method's strengths and limitations in automating clinical knowledge management while striving for a zero-error policy are evaluated, offering insights into their roles in enhancing healthcare through intelligent decision support. The study aims to inform decisions in the development of effective, transparent CDS systems in clinical and patient care settings.