在环孢素A基础上加用海曲泊帕可改善新诊断的输血依赖型非重型再生障碍性贫血患者的反应。 - Suppr

Adding hetrombopag to cyclosporine a improved response of patients with newly diagnosed transfusion-dependent non-severe aplastic anemia.

作者信息

Shen Shupei, Hu Qinglin, Yang Chen, Jiang Zeyu, Chen Miao, Han Bing

机构信息

Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing, 100730, China.

Department of Hematology, Peking Union Medical College Hospital, Chinese Academe of Medical Science, Beijing, 100730, China.

出版信息

Ann Hematol. 2024 Oct;103(10):4247-4249. doi: 10.1007/s00277-024-05941-3. Epub 2024 Aug 23.

DOI:10.1007/s00277-024-05941-3

PMID:39177798

Abstract

摘要

相似文献

Adding hetrombopag to cyclosporine a improved response of patients with newly diagnosed transfusion-dependent non-severe aplastic anemia.

Ann Hematol. 2024 Oct;103(10):4247-4249. doi: 10.1007/s00277-024-05941-3. Epub 2024 Aug 23.

Hetrombopag plus porcine ATG and cyclosporine for the treatment of aplastic anaemia: early outcomes of a prospective pilot study.

Exp Hematol Oncol. 2023 Feb 1;12(1):16. doi: 10.1186/s40164-023-00377-3.

A multicenter phase II study on the efficacy and safety of hetrombopag in patients with severe aplastic anemia refractory to immunosuppressive therapy.

Ther Adv Hematol. 2022 Mar 30;13:20406207221085197. doi: 10.1177/20406207221085197. eCollection 2022.

Iron chelation of hetrombopag in aplastic anemia: a post hoc analysis of a phase II study.

Ann Hematol. 2022 Dec;101(12):2611-2616. doi: 10.1007/s00277-022-04968-8. Epub 2022 Oct 11.

High- vs regular-dose recombinant human thrombopoietin plus cyclosporine A in patients with newly diagnosed non-severe aplastic anemia: a retrospective cohort study.

Hematology. 2024 Dec;29(1):2298523. doi: 10.1080/16078454.2023.2298523. Epub 2023 Dec 29.

The effect of hetrombopag combined with conventional treatment on immune function and quality of life in patients with severe aplastic anemia.

Ann Hematol. 2024 Nov;103(11):4477-4483. doi: 10.1007/s00277-024-05964-w. Epub 2024 Sep 5.

The progression risk factors of children with transfusion-independent non-severe aplastic anemia.

Int J Hematol. 2013 Feb;97(2):210-5. doi: 10.1007/s12185-013-1263-6. Epub 2013 Jan 30.

[Prognostic factors of cyclosporine A combined with androgen in the treatment of transfusion dependent non-severe aplastic anemia].

Zhonghua Xue Ye Xue Za Zhi. 2020 Mar 14;41(3):234-238. doi: 10.3760/cma.j.issn.0253-2727.2020.03.009.

Cyclosporine Therapy in Patients with Transfusion-independent Non-severe Aplastic Anemia: A Retrospective Analysis.

Intern Med. 2019 Feb 1;58(3):355-360. doi: 10.2169/internalmedicine.1372-18. Epub 2018 Aug 24.

A phase I, single-sequence, open-label study to evaluate the drug-drug interaction between hetrombopag and cyclosporine in healthy Chinese subjects.

Br J Clin Pharmacol. 2023 Jul;89(7):2160-2167. doi: 10.1111/bcp.15664. Epub 2023 Feb 20.

本文引用的文献

A multicenter phase II study on the efficacy and safety of hetrombopag in patients with severe aplastic anemia refractory to immunosuppressive therapy.

Ther Adv Hematol. 2022 Mar 30;13:20406207221085197. doi: 10.1177/20406207221085197. eCollection 2022.

Hetrombopag: First Approval.

Drugs. 2021 Sep;81(13):1581-1585. doi: 10.1007/s40265-021-01575-1.

Guidelines for the diagnosis and management of aplastic anaemia.

Br J Haematol. 2009 Oct;147(1):43-70. doi: 10.1111/j.1365-2141.2009.07842.x. Epub 2009 Aug 10.

Natural history of transfusion-independent non-severe aplastic anemia in children.

Int J Hematol. 2009 May;89(4):409-413. doi: 10.1007/s12185-009-0302-9. Epub 2009 Apr 3.

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Adding hetrombopag to cyclosporine a improved response of patients with newly diagnosed transfusion-dependent non-severe aplastic anemia.

作者信息

Shen Shupei, Hu Qinglin, Yang Chen, Jiang Zeyu, Chen Miao, Han Bing

机构信息

Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing, 100730, China.

Department of Hematology, Peking Union Medical College Hospital, Chinese Academe of Medical Science, Beijing, 100730, China.

出版信息

Ann Hematol. 2024 Oct;103(10):4247-4249. doi: 10.1007/s00277-024-05941-3. Epub 2024 Aug 23.

DOI:10.1007/s00277-024-05941-3

PMID:39177798

Abstract

摘要

相似文献

Adding hetrombopag to cyclosporine a improved response of patients with newly diagnosed transfusion-dependent non-severe aplastic anemia.

Ann Hematol. 2024 Oct;103(10):4247-4249. doi: 10.1007/s00277-024-05941-3. Epub 2024 Aug 23.

Hetrombopag plus porcine ATG and cyclosporine for the treatment of aplastic anaemia: early outcomes of a prospective pilot study.

Exp Hematol Oncol. 2023 Feb 1;12(1):16. doi: 10.1186/s40164-023-00377-3.

A multicenter phase II study on the efficacy and safety of hetrombopag in patients with severe aplastic anemia refractory to immunosuppressive therapy.

Ther Adv Hematol. 2022 Mar 30;13:20406207221085197. doi: 10.1177/20406207221085197. eCollection 2022.

Iron chelation of hetrombopag in aplastic anemia: a post hoc analysis of a phase II study.

Ann Hematol. 2022 Dec;101(12):2611-2616. doi: 10.1007/s00277-022-04968-8. Epub 2022 Oct 11.

High- vs regular-dose recombinant human thrombopoietin plus cyclosporine A in patients with newly diagnosed non-severe aplastic anemia: a retrospective cohort study.

Hematology. 2024 Dec;29(1):2298523. doi: 10.1080/16078454.2023.2298523. Epub 2023 Dec 29.

The effect of hetrombopag combined with conventional treatment on immune function and quality of life in patients with severe aplastic anemia.

Ann Hematol. 2024 Nov;103(11):4477-4483. doi: 10.1007/s00277-024-05964-w. Epub 2024 Sep 5.

The progression risk factors of children with transfusion-independent non-severe aplastic anemia.

Int J Hematol. 2013 Feb;97(2):210-5. doi: 10.1007/s12185-013-1263-6. Epub 2013 Jan 30.

[Prognostic factors of cyclosporine A combined with androgen in the treatment of transfusion dependent non-severe aplastic anemia].

Zhonghua Xue Ye Xue Za Zhi. 2020 Mar 14;41(3):234-238. doi: 10.3760/cma.j.issn.0253-2727.2020.03.009.

Cyclosporine Therapy in Patients with Transfusion-independent Non-severe Aplastic Anemia: A Retrospective Analysis.

Intern Med. 2019 Feb 1;58(3):355-360. doi: 10.2169/internalmedicine.1372-18. Epub 2018 Aug 24.

A phase I, single-sequence, open-label study to evaluate the drug-drug interaction between hetrombopag and cyclosporine in healthy Chinese subjects.

Br J Clin Pharmacol. 2023 Jul;89(7):2160-2167. doi: 10.1111/bcp.15664. Epub 2023 Feb 20.

本文引用的文献

A multicenter phase II study on the efficacy and safety of hetrombopag in patients with severe aplastic anemia refractory to immunosuppressive therapy.

Ther Adv Hematol. 2022 Mar 30;13:20406207221085197. doi: 10.1177/20406207221085197. eCollection 2022.

Hetrombopag: First Approval.

Drugs. 2021 Sep;81(13):1581-1585. doi: 10.1007/s40265-021-01575-1.

Guidelines for the diagnosis and management of aplastic anaemia.

Br J Haematol. 2009 Oct;147(1):43-70. doi: 10.1111/j.1365-2141.2009.07842.x. Epub 2009 Aug 10.

Natural history of transfusion-independent non-severe aplastic anemia in children.

Int J Hematol. 2009 May;89(4):409-413. doi: 10.1007/s12185-009-0302-9. Epub 2009 Apr 3.

Adding hetrombopag to cyclosporine a improved response of patients with newly diagnosed transfusion-dependent non-severe aplastic anemia.

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Adding hetrombopag to cyclosporine a improved response of patients with newly diagnosed transfusion-dependent non-severe aplastic anemia.

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