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智力残疾者的挑战性行为、限制措施的应用和精神药物处方

Challenging behaviour, the application of restrictive measures and psychotropic drug prescription in people with intellectual disabilities.

机构信息

GGZ Drenthe, Department of Centre for Intellectual Disability and Mental Health, P.O. Box 30007, Assen 9400 RA, the Netherlands.

University of Groningen, University Medical Centre Groningen, Department of Primary and Long-term Care, P.O. Box 196, Groningen 9700 AD, the Netherlands.

出版信息

Res Dev Disabil. 2024 Oct;153:104824. doi: 10.1016/j.ridd.2024.104824. Epub 2024 Aug 22.

Abstract

BACKGROUND

Prescribing of psychotropic drugs (PDs) and applying restrictive measures are both frequently used in managing challenging behaviour of people with intellectual disabilities (ID), which is not always according to guidelines or good clinical practice.

AIMS

This study aimed to investigate the potential triangular relationship between challenging behaviour, the application of restrictive measures and PD prescription.

METHODS AND PROCEDURES

In this cross-sectional study, data on challenging behaviour, PD prescription and restrictive measures were collected. We defined and compared four mutually exclusive groups of participants.

OUTCOMES AND RESULTS

Challenging behaviour in the group in whom one or more PD were prescribed as a restrictive measures (PDRM) was more severe than in the other three groups. More severe challenging behaviour, a higher number of antipsychotics, antidepressants and anxiolytics/hypnotics prescriptions, a lower dosage, and more application of domotics as restrictive measure was shown in the PDRM compared to the group in whom PDs were prescribed according to guidelines (PDNRM).

CONCLUSIONS AND IMPLICATIONS

We did not find indications for a triangular relationship of challenging behaviour, the application of restrictive measures and PD prescriptions. Future longitudinal research is needed to better understand this complex relationship and should investigate the indication and the effect of treatment. WHAT THIS PAPER ADDS?: This study is a first exploration of the potential triangular relationship between symptoms of challenging behaviour, psychotropic drug (PD) prescription, and the application of restrictive measures. Prescribing PDs and applying restrictive measures are two interventions which are commonly used to manage challenging behaviour in people with intellectual disabilities. Both have been subject of research separately in recent years. However, it is conceivable that the PD prescription in treatments for challenging behaviour could be a substitute for another form of a restrictive measure, for example a physical or mechanical restraint. For this purpose, we defined and compared four mutually exclusive groups of participants. We found no indication for this triangular relationship. On the other hand, we found the highest severity of challenging behaviour in the group who used PDs as restrictive measure next to other restrictive measures. Our results may suggest that both prescribing PDs and applying non-pharmacological restrictive measures are used simultaneously in managing challenging behaviour, are not sufficiently implemented or effective.

摘要

背景

在管理智障人士的挑战性行为时,经常同时使用精神药物(PD)处方和限制措施,但这些做法并不总是符合指南或良好临床实践。

目的

本研究旨在调查挑战性行为、限制措施应用与 PD 处方之间潜在的三角关系。

方法和程序

在这项横断面研究中,收集了关于挑战性行为、PD 处方和限制措施的数据。我们定义并比较了四个相互排斥的参与者组。

结果和结论

在因限制措施而开出一种或多种 PD 的组(PDRM)中,挑战性行为比其他三组更严重。与根据指南开出 PD(PDNRM)的组相比,PDRM 组的挑战性行为更严重,抗精神病药、抗抑郁药和镇静催眠药处方更多,剂量更低,并且更多地使用家庭自动化作为限制措施。我们没有发现挑战性行为、限制措施应用和 PD 处方之间存在三角关系的迹象。未来需要进行纵向研究,以更好地理解这种复杂的关系,并应调查治疗的适应证和效果。

本文增加了什么?:本研究首次探索了挑战性行为、精神药物(PD)处方和限制措施应用之间潜在的三角关系。在智障人士中,处方 PD 和应用限制措施是两种常用于管理挑战性行为的干预措施。近年来,这两种干预措施都分别受到了研究。然而,可以想象的是,PD 处方可能是治疗挑战性行为的另一种限制措施的替代品,例如身体或机械约束。为此,我们定义并比较了四个相互排斥的参与者组。我们没有发现这种三角关系的迹象。另一方面,我们发现使用 PD 作为限制措施的组的挑战性行为严重程度最高,仅次于其他限制措施。我们的结果可能表明,在管理挑战性行为时,同时使用 PD 处方和非药物限制措施,且这些措施的实施或效果并不充分。

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