Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland.
Department of Urology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Eur Urol Focus. 2024 Sep;10(5):702-705. doi: 10.1016/j.euf.2024.08.003. Epub 2024 Aug 23.
Urinary tract infections (UTIs) are frequently associated with lower urinary tract dysfunction (LUTD). Urodynamic investigation (UDI) is the gold standard for assessing LUTD, but its value in identifying UTI risk factors remains underexplored. Studies have shown high rates of storage and voiding dysfunction in patients with recurrent UTIs, suggesting a causal link between LUTD and UTIs. Specific UDI findings, such as low bladder capacity, high detrusor pressures, and detrusor overactivity, have been associated with greater UTI risk, especially in kidney transplant recipients and infants. However, the current evidence is limited by the lack of control groups and therapeutic interventions, making it difficult to draw definitive conclusions. Further well-designed studies are needed to determine if UDI-guided therapies can improve UTI management outcomes. PATIENT SUMMARY: Urinary infections are often linked to problems with the lower urinary tract. Tests that measure lower urinary tract function can help in identifying these issues. More research is needed to see if treating bladder problems can prevent urinary infections.
尿路感染(UTI)常与下尿路功能障碍(LUTD)有关。尿动力学检查(UDI)是评估 LUTD 的金标准,但它在确定 UTI 危险因素方面的价值仍未得到充分探索。研究表明,复发性 UTI 患者存在较高的储尿和排尿功能障碍,提示 LUTD 与 UTI 之间存在因果关系。特定的 UDI 发现,如膀胱容量低、逼尿肌压力高和逼尿肌过度活动,与更大的 UTI 风险相关,尤其是在肾移植受者和婴儿中。然而,目前的证据受到缺乏对照组和治疗干预的限制,难以得出明确的结论。需要进一步进行精心设计的研究,以确定 UDI 指导的治疗是否可以改善 UTI 管理的结果。患者总结:尿路感染常与下尿路问题有关。测量下尿路功能的测试有助于识别这些问题。需要更多的研究来确定治疗膀胱问题是否可以预防尿路感染。