锌催化的砜亚胺与羧酸的N-芳酰化反应

Zinc-Catalyzed N-Aroylation of Sulfoximines with Carboxylic Acids.

作者信息

Chen Ze-Wei, Bai Rekha, Annamalai Pratheepkumar, Badsara Satpal Singh, Lee Chin-Fa

机构信息

Department of Chemistry, National Chung Hsing University Institution, Taichung, Taiwan.

MFOS Laboratory, Department of Chemistry, University of Rajasthan, JLN Marg, 302004, Jaipur, Rajasthan, India.

出版信息

Chem Asian J. 2024 Dec 2;19(23):e202400780. doi: 10.1002/asia.202400780. Epub 2024 Oct 22.

DOI:10.1002/asia.202400780

PMID:39180462

Abstract

A zinc-catalyzed C(sp)-N dehydrative cross-coupling between carboxylic acids and NH-sulfoximines to afford N-aroylated sulfoximines under mild reaction conditions is described. Various NH-sulfoximines were coupled with readily available carboxylic acids to provide the corresponding N-aroylated sulfoximines in good to excellent yields.

摘要

描述了一种锌催化的羧酸与NH-亚磺酰亚胺之间的C(sp)-N脱水交叉偶联反应，该反应在温和的反应条件下可生成N-芳酰化亚磺酰亚胺。各种NH-亚磺酰亚胺与易得的羧酸偶联，以良好至优异的产率提供相应的N-芳酰化亚磺酰亚胺。