Department of Surgery, King Edward Medical University, Lahore, Pakistan.
Department of Surgery, King Edward Medical University, Lahore, Pakistan.
J Surg Res. 2024 Oct;302:593-605. doi: 10.1016/j.jss.2024.07.107. Epub 2024 Aug 23.
Acute subdural hemorrhage (ASDH) from traumatic brain injury is a life-threatening situation, often requiring surgical intervention. This meta-analysis is done to update the literature regarding the choice of procedure for the treatment of ASDH.
PubMed, Scopus, and Cochrane were searched from the year 2000 up to September 2023. Randomized controlled trials and observational studies were included. The odds ratio with 95% confidence interval (CI) mean difference and standardized mean difference were calculated for dichotomous and continuous outcomes, respectively.
A total of 14 studies comprising 4686 patients were included in the analysis. Pooled Glasgow Outcome Scale/Extended Glasgow Outcome Scale scores were compared based on their means, with the craniotomy (CO) group having better mean scores than decompressive craniectomy (DC) (standardized mean difference -0.37, 95% CI -0.68 to -0.06, P = 0.02). The risk for poor outcomes was statistically greater in the DC group compared to the CO group (1.32, 95% CI 1.05-1.66, P value = 0.02). There were fewer residual subdural hematoma cases in the DC group as compared to CO (odds ratio 0.40, 95% CI 0.22-0.73, P value < 0.005).
Our meta-analysis showed that the ASDH patients had better functional outcomes when treated with CO as compared to DC. However, there were fewer odds of residual subdural hematoma with DC.
创伤性脑损伤导致的急性硬脑膜下血肿(ASDH)是一种危及生命的情况,通常需要手术干预。本荟萃分析旨在更新关于 ASDH 治疗方法选择的文献。
从 2000 年到 2023 年 9 月,我们在 PubMed、Scopus 和 Cochrane 上进行了搜索。纳入了随机对照试验和观察性研究。使用 95%置信区间(CI)的比值比(OR)和均数差值及标准化均数差值分别计算二分类和连续结局的结果。
共有 14 项研究纳入了 4686 名患者。根据平均值比较了开颅术(CO)组和去骨瓣减压术(DC)组的格拉斯哥预后量表/扩展格拉斯哥预后量表评分,CO 组的平均评分优于 DC 组(标准化均数差值 -0.37,95%CI -0.68 至 -0.06,P=0.02)。与 CO 组相比,DC 组不良结局的风险更高(OR 1.32,95%CI 1.05-1.66,P 值=0.02)。与 CO 组相比,DC 组残余硬脑膜下血肿的病例较少(OR 0.40,95%CI 0.22-0.73,P 值<0.005)。
我们的荟萃分析表明,与 DC 相比,ASDH 患者接受 CO 治疗时功能结局更好。然而,与 CO 相比,DC 残余硬脑膜下血肿的几率较低。