Jagdev Ambroise, Malard Olivier, Lépine Charles, Lesclous Philippe
Department of Oral Surgery, Nantes University Hospital, 1 place Alexis Ricordeau, 44000 Nantes, France.
Department of Otorhinolaryngology, Head and Neck Surgery, Nantes University Hospital, 1 place Alexis Ricordeau, 44000 Nantes, France.
J Stomatol Oral Maxillofac Surg. 2025 Feb;126(1):102020. doi: 10.1016/j.jormas.2024.102020. Epub 2024 Aug 23.
Calcified epithelial odontogenic tumor (CEOT) with extension to the maxillary, ethmoid and sphenoid sinuses is currently unreported. This extension poses a challenge for effective treatment, as CEOT is a benign neoplasm with contreversial potential aggressiveness. We report a case of CEOT that was previously misdiagnosed as an inverted papilloma. A segmental resection of the part of the tumor responsible for the symptoms was performed. Histology revealed polyhedral epithelial cells within an amorphous eosinophilic hyaline material containing round calcified structures and confirmed the diagnosis of CEOT. Postoperative CT Scan showed the partial resection of the tumoral process. A mixed radiolucent/radiopaque aspect of the remaining CEOT was clearly discernible. The patient was warned that due to the incomplete excision of the tumoral process, the risk of recurrence was significant and that a close clinical and radiological follow-up every 6 months was mandatory for a long time.
钙化上皮性牙源性肿瘤(CEOT)累及上颌窦、筛窦和蝶窦的情况目前尚无报道。这种累及对有效治疗构成了挑战,因为CEOT是一种具有潜在侵袭性争议的良性肿瘤。我们报告一例曾被误诊为内翻性乳头状瘤的CEOT病例。对引起症状的肿瘤部分进行了节段性切除。组织学检查显示多面形上皮细胞位于含有圆形钙化结构的无定形嗜酸性透明物质内,确诊为CEOT。术后CT扫描显示肿瘤部分切除。剩余CEOT呈现出混合性透射线/阻射线表现,清晰可见。患者被告知,由于肿瘤切除不完全,复发风险很大,长期每6个月进行密切的临床和影像学随访是必要的。