Colombani P M, Dudgeon D L, Buck J R, Miller D M, Ghory M J, Buckloo C, Haller J A
JPEN J Parenter Enteral Nutr. 1985 Jan-Feb;9(1):38-41. doi: 10.1177/014860718500900138.
During a 21-month period, 50 consecutive pediatric oncology patients undergoing bone marrow transplantation and/or cytoreductive chemotherapy had 61 silastic central venous catheters placed to facilitate their therapy. All catheters were used for medications, routine blood sampling, and transfusions, with 45% also used for hyperalimentation and 57% used for bone marrow transplantation. Catheters were utilized during both inpatient and outpatient therapy periods. Total catheter days numbered 8455, an average of 139 days per catheter. Forty-seven catheters (77%) were removed electively or were in place at time of patient death. Seven were removed for mechanical complications (1/1409 catheter days). Four additional episodes of presumed catheter sepsis were managed with antibiotics and did not require catheter removal (40% of septic episodes). One catheter is still in place after 585 days. Complication rates were not influenced by this multiple use protocol. With standardized catheter care and surveillance, multipurpose, long-term central venous access can be safely utilized in the immunosuppressed pediatric patient.
在21个月的时间里，50例连续接受骨髓移植和/或减瘤化疗的儿科肿瘤患者共置入了61根硅橡胶中心静脉导管，以方便治疗。所有导管均用于给药、常规采血和输血，45%的导管还用于胃肠外营养，57%用于骨髓移植。导管在住院和门诊治疗期间均有使用。导管总使用天数为8455天，平均每根导管使用139天。47根导管（77%）被选择性拔除或在患者死亡时仍留置。7根因机械并发症而拔除（每1409个导管日中有1根）。另外4例疑似导管败血症经抗生素治疗，无需拔除导管（占败血症病例的40%）。1根导管在585天后仍留置。并发症发生率不受这种多用途方案的影响。通过标准化的导管护理和监测，多用途、长期的中心静脉通路可安全地用于免疫抑制的儿科患者。
