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提高脑出血预后准确性:血清分泌素和新兴生物标志物的作用

"Enhancing prognostic accuracy in intracerebral hemorrhage: the role of serum secretoneurin and emerging biomarkers".

机构信息

Islamic International Medical College, Peshawar Road, Rawalpindi, Punjab, Pakistan.

出版信息

Neurosurg Rev. 2024 Aug 26;47(1):478. doi: 10.1007/s10143-024-02728-y.

Abstract

Intracerebral hemorrhage (ICH) is a severe stroke type with high mortality and disability rates, and traditional prognostic tools like the Glasgow Coma Scale (GCS) have limited predictive power. Emerging research suggests that serum secretoneurin could serve as a promising biomarker for ICH. Elevated secretoneurin levels have been associated with poorer outcomes and may offer more precise prognostic insights compared to conventional methods. This biomarker's potential to enhance outcome prediction underscores the need for further research to validate its efficacy and integrate it into clinical practice. Future studies should also explore additional biomarkers and advanced predictive models.

摘要

脑出血 (ICH) 是一种严重的中风类型,死亡率和残疾率都很高,传统的预后工具如格拉斯哥昏迷量表 (GCS) 的预测能力有限。新兴研究表明,血清分泌素原可能是 ICH 的一种很有前途的生物标志物。升高的分泌素原水平与较差的预后相关,与传统方法相比,可能提供更精确的预后见解。该生物标志物在增强预后预测方面的潜力突出了进一步研究其疗效并将其纳入临床实践的必要性。未来的研究还应探索其他生物标志物和先进的预测模型。

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