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经皮椎体后凸成形术后非闭塞性肠系膜缺血:病例报告。

Nonocclusive mesenteric ischemia after percutaneous kyphoplasty: A case report.

机构信息

Department of Orthopedic Trauma, Aviation General Hospital, Beijing, PR China.

Department of Radiology, Aviation General Hospital, Beijing, PR China.

出版信息

Medicine (Baltimore). 2024 Aug 23;103(34):e39390. doi: 10.1097/MD.0000000000039390.

Abstract

RATIONALE

Percutaneous kyphoplasty (PKP) is a minimally invasive technique employed for treating vertebral compression fractures. Although PKP is simple and relatively safe, severe complications are possible. Here, we report a new, severe complication linked to this procedure, namely nonocclusive mesenteric ischemia (NOMI).

PATIENT CONCERNS

An 83-year-old female patient, previously in good health, fell backward, landing on her buttocks, and subsequently experienced persistent low-back pain that exacerbated during turning or sitting up.

DIAGNOSES

Lumbar spine radiography revealed wedge deformity of the L1 vertebral body. Lumbar spine magnetic resonance imaging indicated a fresh compression fracture of the L1 vertebral body.

INTERVENTIONS

On the 2nd day following the trauma, the patient underwent PKP under local anesthesia. Anesthesia was satisfactory, and the procedure progressed smoothly.

OUTCOMES

The patient experienced mild discomfort in the right abdomen within the 1st hour to 3 days postoperatively, mild abdominal distension on the 4th day, and sudden severe abdominal pain on the 5th day. Immediate abdominal computed tomography revealed ischemic changes in the ascending colon and hepatic flexure, accompanied by hepatic portal venous gas. An hour later, abdominal pain spontaneously subsided. Approximately 5 hours later, an enhanced abdominal computed tomography revealed no filling defects in the mesenteric vasculature, absence of luminal narrowing or occlusion, enhanced intestinal walls, and a notable improvement in hepatic portal venous gas. Considering NOMI and ischemia related to superior mesenteric artery spasm, vasodilator therapy (papaverine hydrochloride) was initiated, leading to favorable outcomes. On day 17, pathological examination of the hepatic flexure revealed moderate, acute, and chronic mucosal inflammation, along with interstitial fibrous tissue proliferation, providing clear evidence supporting ischemic changes. She was discharged on day 18 after a successful recovery.

LESSONS

The occurrence of NOMI after PKP is uncommon. Yet, once it happens, delayed diagnosis or misdiagnosis can lead to serious consequences such as intestinal necrosis and abdominal infection, even endangering the patient's life. We currently lack experience in preventing this complication, but timely diagnosis and appropriate intervention are effective measures in treating such complications.

摘要

背景

经皮椎体后凸成形术(PKP)是一种用于治疗椎体压缩性骨折的微创技术。虽然 PKP 简单且相对安全,但仍可能出现严重并发症。在这里,我们报告了一种与该手术相关的新的严重并发症,即非闭塞性肠系膜缺血(NOMI)。

病例介绍

一名 83 岁女性,既往健康,摔倒后臀部着地,随后出现持续性腰痛,在转身或坐起时加重。

影像学检查

腰椎 X 线片显示 L1 椎体楔形改变。腰椎磁共振成像(MRI)提示 L1 椎体新鲜压缩性骨折。

治疗经过

受伤后第 2 天行 PKP,在局部麻醉下进行。麻醉效果满意,手术过程顺利。

术后情况

术后 1 至 3 天内,患者右腹部轻度不适,第 4 天出现轻度腹胀,第 5 天突然出现严重腹痛。立即行腹部 CT 检查显示升结肠和结肠肝曲缺血改变,伴有肝门静脉积气。1 小时后腹痛自行缓解。约 5 小时后,增强腹部 CT 示肠系膜血管无充盈缺损,肠腔无狭窄或闭塞,肠壁强化,肝门静脉积气明显改善。考虑 NOMI 和与肠系膜上动脉痉挛相关的缺血,给予血管扩张剂(盐酸罂粟碱)治疗,结果良好。第 17 天,横结肠活检显示中度、急性和慢性黏膜炎症,伴有间质纤维组织增生,明确支持缺血改变。患者恢复良好,于第 18 天出院。

教训

PKP 后发生 NOMI 并不常见。然而,一旦发生,延迟诊断或误诊可能导致严重后果,如肠坏死和腹部感染,甚至危及患者生命。我们目前在预防这种并发症方面经验不足,但及时诊断和适当干预是治疗此类并发症的有效措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42f6/11346888/0f8e3a123a8d/medi-103-e39390-g001.jpg

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