Sarwar M, Virapongse C, Carbo P
AJNR Am J Neuroradiol. 1985 Jan-Feb;6(1):19-22.
Prior efforts at experimental production of superior sagittal sinus (SSS) thrombosis generally have been unsuccessful. An experimental method was devised of inducing SSS thrombosis in the dog by use of double-lumen balloon catheters. Two balloon catheters, introduced into each internal jugular vein, are finally positioned at the torcular Herophili. The resulting stasis in the SSS, initiated by the inflated balloons, is augmented by injecting thrombin into the SSS. The stasis and the intraluminal thrombin cause thrombosis, which can be visualized on computed tomography (CT). This method may be used to study the natural history of SSS thrombosis as well as establish its CT and magnetic resonance imaging characteristics.
以往在实验性制造上矢状窦(SSS)血栓形成方面的努力通常都未成功。设计了一种利用双腔球囊导管在犬体内诱导SSS血栓形成的实验方法。将两根球囊导管插入每条颈内静脉,最终放置在窦汇处。由膨胀的球囊引发的SSS内血流淤滞,通过向SSS内注射凝血酶而加剧。血流淤滞和管腔内的凝血酶导致血栓形成,这在计算机断层扫描(CT)上可以显现出来。该方法可用于研究SSS血栓形成的自然病程,以及确定其CT和磁共振成像特征。