Mohsen Karim Abdel, AbdEl-Raouf Mona Nady, Makram Kirolos, ElKassaby Marwa, Khairy Maggie, AbdelAziz Mahmoud, El-Messiry Hend, Gaber Ramy
Department of Oral and Maxillofacial Surgery, Ain Shams University, Cairo, Egypt.
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, October 6 University, 6 October, Egypt.
Ann Maxillofac Surg. 2024 Jan-Jun;14(1):21-26. doi: 10.4103/ams.ams_165_23. Epub 2024 Feb 6.
Early dental implant failure (EDIF) can occur even when optimal materials are used, surgical protocols are strictly followed and the quantity and quality of bone at the recipient site are sufficient. The existence of specific patient-related risk factors require an investigation into the regulatory mechanisms controlling bone metabolism, bone remodelling and bone turnover as well as serum Vitamin D. The implant stability quotient is used as a prognostic indicator for possible implant failure. The aim of the study is to investigate the relationship between serum Vitamin D levels and EDIF.
A total of 143 implant placement sites were identified in 53 patients enrolled in this study. All patients had the assessments of serum Vitamin D levels side by side with assessments of primary and secondary implant stability at proposed implant sites at the time of implant placement and after 12 weeks using a resonance frequency analysis device.
Ten early failures (7%) were recorded. There was no correlation between gender, age, smoking, hyperglycaemia or an increased incidence of early failures. Statistical analysis reported two early failures (4.5%) in patients with serum levels of Vitamin D >30 ng/mL, two early failures (2.3%) in patients with levels between 10 and 30 ng/mL and six early failures (46.2%) in patients with levels <10 ng/mL.
The role of Vitamin D as a risk factor for early implant failure should be considered in patients with Vitamin D deficiency. The incidence of early implant failures was higher in patients with low serum levels of Vitamin D. Patients with low serum Vitamin D levels had a greater rate of early implant failure.
即使使用了最佳材料、严格遵循手术方案且受体部位的骨量和质量充足，早期牙种植体失败（EDIF）仍可能发生。特定的患者相关风险因素的存在需要对控制骨代谢、骨重塑和骨转换以及血清维生素D的调节机制进行研究。种植体稳定性商数被用作可能的种植体失败的预后指标。本研究的目的是调查血清维生素D水平与早期牙种植体失败之间的关系。
本研究纳入了53名患者，共确定了143个种植部位。所有患者在种植时以及12周后，使用共振频率分析装置在拟种植部位同时进行血清维生素D水平评估以及种植体初期和二期稳定性评估。
记录到10例早期失败（7%）。性别、年龄、吸烟、高血糖与早期失败发生率增加之间无相关性。统计分析显示，血清维生素D水平>30 ng/mL的患者中有2例早期失败（4.5%），水平在10至30 ng/mL之间的患者中有2例早期失败（2.3%），水平<10 ng/mL的患者中有6例早期失败（46.2%）。
维生素D缺乏的患者应考虑维生素D作为早期种植体失败风险因素的作用。血清维生素D水平低的患者早期种植体失败的发生率更高。血清维生素D水平低的患者早期种植体失败率更高。
