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Activin A from primary breast tumors generates a pre-metastatic niche by inducing pulmonary fibrosis.

作者信息

Shirakihara Takuya, Orimo Akira

机构信息

Department of Molecular Pathogenesis, Graduate School of Medicine, Juntendo University, Tokyo, Japan.

出版信息

Transl Breast Cancer Res. 2024 Jul 22;5:24. doi: 10.21037/tbcr-24-5. eCollection 2024.

DOI:10.21037/tbcr-24-5
PMID:39184930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11341999/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c70/11341999/124e621cf572/tbcr-05-24-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c70/11341999/124e621cf572/tbcr-05-24-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c70/11341999/124e621cf572/tbcr-05-24-f1.jpg

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本文引用的文献

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Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs.骨肉瘤细胞来源的细胞外囊泡包裹的 S100A11 通过募集粒细胞髓系来源抑制细胞来介导肺转移前微环境的形成。
Cell Rep. 2024 Feb 27;43(2):113751. doi: 10.1016/j.celrep.2024.113751. Epub 2024 Feb 10.
2
Breast Cancer-Secreted Factors Promote Lung Metastasis by Signaling Systemically to Induce a Fibrotic Premetastatic Niche.乳腺癌分泌因子通过全身性信号诱导纤维化前转移龛促进肺转移。
Cancer Res. 2023 Oct 13;83(20):3354-3367. doi: 10.1158/0008-5472.CAN-22-3707.
3
Chemotherapy-induced complement signaling modulates immunosuppression and metastatic relapse in breast cancer.
化疗诱导的补体信号转导调节乳腺癌的免疫抑制和转移复发。
Nat Commun. 2022 Oct 2;13(1):5797. doi: 10.1038/s41467-022-33598-x.
4
Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment.肺成纤维细胞通过重塑局部免疫微环境促进转移前龛的形成。
Immunity. 2022 Aug 9;55(8):1483-1500.e9. doi: 10.1016/j.immuni.2022.07.001. Epub 2022 Jul 30.
5
Lin28B-high breast cancer cells promote immune suppression in the lung pre-metastatic niche via exosomes and support cancer progression.Lin28B 高表达乳腺癌细胞通过外泌体在肺转移前微环境中促进免疫抑制并支持肿瘤进展。
Nat Commun. 2022 Feb 16;13(1):897. doi: 10.1038/s41467-022-28438-x.
6
A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy.肿瘤来源的富含III型胶原蛋白的细胞外基质微环境调节肿瘤细胞休眠。
Nat Cancer. 2022 Jan;3(1):90-107. doi: 10.1038/s43018-021-00291-9. Epub 2021 Dec 13.
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Evolution of fibroblasts in the lung metastatic microenvironment is driven by stage-specific transcriptional plasticity.肺转移微环境中,成纤维细胞的演变由阶段特异性转录可塑性驱动。
Elife. 2021 Jun 25;10:e60745. doi: 10.7554/eLife.60745.
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Metastasis-Initiating Cells and Ecosystems.转移起始细胞和生态系统。
Cancer Discov. 2021 Apr;11(4):971-994. doi: 10.1158/2159-8290.CD-21-0010.
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Cancer Cell. 2020 Jun 8;37(6):800-817.e7. doi: 10.1016/j.ccell.2020.05.005.