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优化眨眼对计算机视觉综合征患者视力及相关参数的影响:一项单盲随机对照试验

The Impact of Optimized Blinking on Vision and Related Parameters in Individuals With Computer Vision Syndrome: A Single-Blind Randomized Controlled Trial.

作者信息

Sadhwani Parul, Cs Lalitha, Dash Shovna, Mohanty Soumyakanta

机构信息

Ophthalmology, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.

出版信息

Cureus. 2024 Aug 24;16(8):e67653. doi: 10.7759/cureus.67653. eCollection 2024 Aug.

Abstract

INTRODUCTION

Computer vision syndrome (CVS) has become a significant issue for individuals working on computers and digital devices for extended periods. The ocular and periocular symptoms and signs associated with CVS are a major concern, affecting individuals physically and financially. Additionally, CVS has been linked to the rapid progression of myopia, exacerbating the situation. Blinking has been one of the major treatment methods for the treatment of CVS. This study presents a unique and novel randomized controlled therapeutic trial that evaluates the impact of extended blinking therapy on eye health and vision, along with other related parameters. Materials and methods: The present study is a randomized controlled trial conducted from September 2022 to April 2024. Participants aged 18-40 with CVS and a computer vision syndrome questionnaire (CVS-Q) score of ≥6, with mild to moderate refractive error (between -6D and +4D), were included. The sample size was determined based on a pilot study, resulting in a minimum required sample size of 36 patients (18 cases and 18 controls). Participants were randomly assigned to either the case (interventional) or control (conventional) group and were followed up for six months. Cases received conventional CVS treatment plus optimized blinking exercises, while controls received conventional therapy only. Comprehensive ocular assessments were conducted bi-monthly over six months, evaluating changes in uncorrected visual acuity (UCVA), refractive error, near point of accommodation (NPA), near point of convergence (NPC), Schirmer's test, and tear film breakup time (TBUT).

RESULTS

The study included 20 patients in the case group and 18 in the control group, primarily aged 20-29 (60.5%). Most patients used laptops for their activities (55.26%). The CVS-Q score significantly decreased in both groups following treatment, with both cases and controls showing significant improvement (p<0.001 for both groups). UCVA in the right eye (RE) and left eye (LE) of the cases improved significantly post-treatment in the interventional group (RE: p=0.002; LE: p<0.001). A significant change in refractive error, which is measured as spherical equivalent (SE), was seen among cases following treatment (RE: p<0.001; LE: p=0.021). Controls showed no significant changes in visual acuity or refractive error. The NPA in the cases improved significantly in the RE (p=0.027) but not in the left. The NPC in the intervention group showed no significant change, while controls showed considerable improvement (p=0.042). Schirmer's test results showed no significant change in either group. However, TBUT in the cases improved significantly (RE: p<0.001; LE: p<0.001). In the controls, TBUT decreased significantly, indicating a deterioration in tear film stability. Asthenopia grades improved considerably in cases, while controls showed only some improvement. Severe symptoms still remained in the control group, emphasizing the potential benefits of the blinking exercise in reducing asthenopia symptoms.

CONCLUSION

Optimized blinking therapy significantly improves vision and refractive error, tear film stability, and discomfort, making it beneficial for chronic computer users to maintain ocular health and enhance productivity and quality of life.

摘要

引言

电脑视觉综合征(CVS)已成为长时间使用电脑和数字设备的人群面临的一个重要问题。与CVS相关的眼部及眼周症状和体征是主要关注点,对个人的身体和经济都有影响。此外,CVS与近视的快速发展有关,使情况更加恶化。眨眼一直是治疗CVS的主要方法之一。本研究提出了一项独特且新颖的随机对照治疗试验,评估延长眨眼疗法对眼部健康和视力以及其他相关参数的影响。

材料与方法

本研究是一项于2022年9月至2024年4月进行的随机对照试验。纳入年龄在18 - 40岁、患有CVS且电脑视觉综合征问卷(CVS - Q)评分≥6、屈光不正为轻度至中度(-6D至+4D)的参与者。样本量根据一项初步研究确定,所需最小样本量为36例患者(18例病例和18例对照)。参与者被随机分配到病例(干预)组或对照(常规)组,并随访六个月。病例组接受常规CVS治疗加优化眨眼练习,而对照组仅接受常规治疗。在六个月内每两个月进行一次全面的眼部评估,评估未矫正视力(UCVA)、屈光不正、调节近点(NPA)、集合近点(NPC)、泪液分泌试验、泪膜破裂时间(TBUT)的变化。

结果

研究包括病例组20例患者和对照组18例患者,主要年龄在20 - 29岁(60.5%)。大多数患者活动时使用笔记本电脑(55.26%)。治疗后两组的CVS - Q评分均显著降低,病例组和对照组均有显著改善(两组p均<0.001)。干预组病例治疗后右眼(RE)和左眼(LE)的UCVA显著改善(RE:p = 0.002;LE:p<0.001)。病例组治疗后屈光不正以等效球镜(SE)衡量有显著变化(RE:p<0.001;LE:p = 0.021)。对照组的视力或屈光不正无显著变化。病例组右眼的NPA显著改善(p = 0.027),左眼未改善。干预组的NPC无显著变化,而对照组有显著改善(p = 0.042)。泪液分泌试验结果两组均无显著变化。然而,病例组的TBUT显著改善(RE:p<0.001;LE:p<0.001)。对照组的TBUT显著降低,表明泪膜稳定性恶化。病例组的视疲劳等级有显著改善,而对照组仅有一些改善。对照组仍有严重症状,强调了眨眼练习在减轻视疲劳症状方面的潜在益处。

结论

优化眨眼疗法显著改善视力、屈光不正、泪膜稳定性和不适感,有利于慢性电脑使用者维持眼部健康并提高生产力和生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8554/11345033/0abc2ec0ae9c/cureus-0016-00000067653-i01.jpg

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