• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Statins Inhibit Cutaneous Squamous Cell Carcinoma Cells.

作者信息

Hackett Asher, Cohen Avi Adam, Frenkel Rutenberg Tal, Hodak Emmilia, Moyal Lilach, Atzmony Lihi

机构信息

Division of Dermatology, Rabin Medical Center, Petah-Tikva, Israel.

Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel; Department of Plastic surgery, Rabin Medical Center, Petah-Tikva, Israel.

出版信息

Acta Derm Venereol. 2024 Aug 25;104:adv25097. doi: 10.2340/actadv.v104.25097.

DOI:10.2340/actadv.v104.25097
PMID:39185545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11367778/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2dd2/11367778/5c968eeecb37/ActaDV-104-25097-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2dd2/11367778/5c968eeecb37/ActaDV-104-25097-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2dd2/11367778/5c968eeecb37/ActaDV-104-25097-g001.jpg

相似文献

1
Statins Inhibit Cutaneous Squamous Cell Carcinoma Cells.他汀类药物抑制皮肤鳞状细胞癌细胞。
Acta Derm Venereol. 2024 Aug 25;104:adv25097. doi: 10.2340/actadv.v104.25097.
2
The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells.3-羟基-3-甲基戊二酰辅酶A还原酶抑制剂,辛伐他汀、洛伐他汀和美伐他汀可抑制黑色素瘤细胞的增殖和侵袭。
BMC Cancer. 2008 Jan 16;8:9. doi: 10.1186/1471-2407-8-9.
3
Fibroblast growth factor receptor promotes progression of cutaneous squamous cell carcinoma.成纤维细胞生长因子受体促进皮肤鳞状细胞癌的进展。
Mol Carcinog. 2019 Oct;58(10):1715-1725. doi: 10.1002/mc.23012. Epub 2019 Jun 29.
4
In vitro Anti-Tumor Effects of Statins on Head and Neck Squamous Cell Carcinoma: A Systematic Review.他汀类药物对头颈部鳞状细胞癌的体外抗肿瘤作用:一项系统评价
PLoS One. 2015 Jun 22;10(6):e0130476. doi: 10.1371/journal.pone.0130476. eCollection 2015.
5
Novel treatments using PD1 inhibitors for advanced and metastatic cutaneous squamous cell carcinoma.使用PD1抑制剂治疗晚期和转移性皮肤鳞状细胞癌的新型疗法。
Expert Rev Anticancer Ther. 2020 Oct;20(10):819-822. doi: 10.1080/14737140.2020.1812389. Epub 2020 Sep 16.
6
Topical 5-fluorouracil elicits regressions of BRAF inhibitor-induced cutaneous squamous cell carcinoma.局部应用5-氟尿嘧啶可使BRAF抑制剂诱导的皮肤鳞状细胞癌消退。
J Invest Dermatol. 2013 Jan;133(1):274-6. doi: 10.1038/jid.2012.268. Epub 2012 Aug 16.
7
Epidermal growth factor receptor inhibition by anti-CD147 therapy in cutaneous squamous cell carcinoma.抗CD147疗法对皮肤鳞状细胞癌中表皮生长因子受体的抑制作用
Head Neck. 2016 Feb;38(2):247-52. doi: 10.1002/hed.23885. Epub 2015 Jun 16.
8
Proteome and phosphoproteome reveal mechanisms of action of atorvastatin against esophageal squamous cell carcinoma.蛋白质组和磷酸化蛋白质组揭示阿托伐他汀抗食管鳞状细胞癌的作用机制。
Aging (Albany NY). 2019 Nov 7;11(21):9530-9543. doi: 10.18632/aging.102402.
9
Novel synthetic inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity that inhibit tumor cell proliferation and are structurally unrelated to existing statins.新型3-羟基-3-甲基戊二酰辅酶A(HMG-CoA)还原酶活性抑制剂,可抑制肿瘤细胞增殖,且在结构上与现有他汀类药物无关。
Int J Mol Med. 2009 Nov;24(5):633-43. doi: 10.3892/ijmm_00000274.
10
Mevalonate pathway is a therapeutic target in esophageal squamous cell carcinoma.甲羟戊酸途径是食管鳞状细胞癌的一个治疗靶点。
Tumour Biol. 2013 Feb;34(1):429-35. doi: 10.1007/s13277-012-0567-0. Epub 2012 Nov 21.

本文引用的文献

1
Statin Medication Improves Five-Year Survival Rates in Patients with Head and Neck Cancer: A Retrospective Case-Control Study of about 100,000 Patients.他汀类药物可提高头颈癌患者的五年生存率:一项对约10万名患者的回顾性病例对照研究。
Cancers (Basel). 2023 Jun 7;15(12):3093. doi: 10.3390/cancers15123093.
2
Safety and Efficacy of Topical Lovastatin Plus Cholesterol Cream vs Topical Lovastatin Cream Alone for the Treatment of Disseminated Superficial Actinic Porokeratosis: A Randomized Clinical Trial.局部洛伐他汀联合胆固醇乳膏与单独使用局部洛伐他汀乳膏治疗播散性浅表性光线性汗孔角化病的疗效和安全性:一项随机临床试验。
JAMA Dermatol. 2023 May 1;159(5):488-495. doi: 10.1001/jamadermatol.2023.0205.
3
Therapeutic targeting of the mevalonate-geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer.
使用他汀类药物对甲羟戊酸-香叶基香叶基二磷酸途径进行治疗性靶向可克服小细胞肺癌的化疗耐药性。
Nat Cancer. 2022 May;3(5):614-628. doi: 10.1038/s43018-022-00358-1. Epub 2022 Apr 21.
4
Guidelines of care for the management of actinic keratosis.光化性角化病治疗管理指南。
J Am Acad Dermatol. 2021 Oct;85(4):e209-e233. doi: 10.1016/j.jaad.2021.02.082. Epub 2021 Apr 2.
5
The Innovative Potential of Statins in Cancer: New Targets for New Therapies.他汀类药物在癌症治疗中的创新潜力:新疗法的新靶点
Front Chem. 2020 Jun 18;8:516. doi: 10.3389/fchem.2020.00516. eCollection 2020.
6
Topical cholesterol/lovastatin for the treatment of porokeratosis: A pathogenesis-directed therapy.局部应用胆固醇/洛伐他汀治疗掌跖角化病:一种针对发病机制的治疗方法。
J Am Acad Dermatol. 2020 Jan;82(1):123-131. doi: 10.1016/j.jaad.2019.08.043. Epub 2019 Aug 23.
7
Statin use and non-melanoma skin cancer risk: a meta-analysis of randomized controlled trials and observational studies.他汀类药物的使用与非黑色素瘤皮肤癌风险:一项对随机对照试验和观察性研究的荟萃分析。
Oncotarget. 2017 Aug 8;8(43):75411-75417. doi: 10.18632/oncotarget.20034. eCollection 2017 Sep 26.
8
Protein prenylation: unique fats make their mark on biology.蛋白质异戊二烯化:独特的脂肪在生物学中留下印记。
Nat Rev Mol Cell Biol. 2016 Feb;17(2):110-22. doi: 10.1038/nrm.2015.11. Epub 2016 Jan 21.
9
Mevalonate Pathway and Human Cancers.甲羟戊酸途径与人类癌症
Curr Mol Pharmacol. 2017;10(2):77-85. doi: 10.2174/1874467209666160112123205.
10
Relation of statin use with non-melanoma skin cancer: prospective results from the Women's Health Initiative.他汀类药物使用与非黑色素瘤皮肤癌的关系:女性健康倡议的前瞻性结果。
Br J Cancer. 2016 Feb 2;114(3):314-20. doi: 10.1038/bjc.2015.376. Epub 2016 Jan 7.