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吸气肌训练对心脏手术后结局的影响:随机对照试验的综合荟萃分析。

Effect of Inspiratory Muscle Training on Outcomes After Cardiac Surgery: A Comprehensive Meta-Analysis of Randomized Controlled Trials.

机构信息

Author Affiliations: Cardiorpulmonary Rehabilitation Ward, Zhejiang Rehabilitation Medical Center (The Affiliated Rehabilitation Hospital of Zhejiang Chinese Medical University), Hangzhou, Zhejiang Province, China; and Rehabilitation Medicine Department 2, The Third Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine, Hangzhou, Zhejiang Province, China.

出版信息

J Cardiopulm Rehabil Prev. 2024 Sep 1;44(5):324-332. doi: 10.1097/HCR.0000000000000890. Epub 2024 Sep 3.

Abstract

PURPOSE

Inspiratory muscle training (IMT) has emerged as a potential intervention to improve respiratory outcomes for patients undergoing cardiac surgery. However, the extent of the IMT effects on preoperative and postoperative respiratory metrics remains uncertain. Hence, we designed this study to determine the effects of IMT on various outcomes of patients undergoing cardiac surgery.

METHODS

We conducted a comprehensive meta-analysis of studies evaluating the impact of preoperative and postoperative IMT on various respiratory variables and postsurgical outcomes. We synthesized data from multiple studies, encompassing diverse patient populations and IMT protocols. The key outcomes included the maximal inspiratory pressure (MIP), forced expiratory volume in 1 sec (FEV1), forced vital capacity (FVC), and others.

RESULTS

Our meta-analysis results showed that preoperative IMT significantly improved the MIP values with a pooled standard mean difference (SMD) of 0.62. The hospital stay length was also reduced with a SMD of - 0.4. Other variables such as FEV1 and FVC also improved significantly. Postoperative IMT improved the MIP and peak flow rate values, but the evidence was less robust than with preoperative interventions. We observed high heterogeneity across studies for several outcomes and found evidence of publication bias for some postoperative measures.

CONCLUSION

Both preoperative and postoperative IMT offer benefits for patients undergoing operations, especially by enhancing respiratory muscle strength and potentially reducing hospital stays. However, the presence of heterogeneity and publication bias underscores the need for further standardized research to consolidate these findings and standardize IMT protocols for optimal patient outcomes.

摘要

目的

吸气肌训练(IMT)已成为一种改善心脏手术患者呼吸结果的潜在干预手段。然而,IMT 对术前和术后呼吸指标的影响程度仍不确定。因此,我们设计了这项研究来确定 IMT 对接受心脏手术患者的各种结果的影响。

方法

我们对评估术前和术后 IMT 对各种呼吸变量和术后结果影响的研究进行了全面的荟萃分析。我们综合了来自多个研究的数据,这些研究涵盖了不同的患者人群和 IMT 方案。主要结果包括最大吸气压力(MIP)、1 秒用力呼气量(FEV1)、用力肺活量(FVC)等。

结果

我们的荟萃分析结果表明,术前 IMT 显著提高了 MIP 值,合并的标准均数差(SMD)为 0.62。住院时间也缩短了,SMD 为-0.4。其他变量如 FEV1 和 FVC 也有显著改善。术后 IMT 改善了 MIP 和峰值流量值,但证据不如术前干预有力。我们观察到几个结果的研究之间存在高度异质性,并发现一些术后测量存在发表偏倚的证据。

结论

术前和术后 IMT 都为接受手术的患者带来了益处,特别是通过增强呼吸肌力量,可能减少住院时间。然而,异质性和发表偏倚的存在突出表明需要进一步进行标准化研究,以整合这些发现并为最佳患者结果标准化 IMT 方案。

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