Kleiman Evan M, Bentley Kate H, Jaroszewski Adam C, Maimone Joseph S, Fortgang Rebecca G, Zuromski Kelly L, Kilbury Erin N, Stein Michelle B, Beck Stuart, Huffman Jeff C, Nock Matthew K
Arch Suicide Res. 2024 Aug 26:1-18. doi: 10.1080/13811118.2024.2391293.
The weeks following an inpatient psychiatric hospitalization are known to be the highest-risk time for suicide. Interventions are needed that are well-matched to the dynamic nature of suicidal thoughts and easily implementable during this high-risk time. We sought to determine the feasibility and acceptability of a novel registered clinical trial that combined three brief in-person sessions to teach core cognitive-behavioral therapy (CBT) skills during hospitalization followed by smartphone-based ecological momentary intervention (EMI) to facilitate real-time practice of the emotion management skills during the 28 days after hospital discharge. Results from this pilot study ( = 26) supported some aspects of feasibility and acceptability. Regarding feasibility, 14.7% of all screened inpatients met study eligibility criteria. Half (50.3%) of those who were ineligible were ineligible because they were not part of the population for whom this treatment was designed (e.g., symptoms such as psychosis rendered them ineligible for the current study). Those who were otherwise eligible based on symptoms were primarily ineligible due to inpatient stays that were too short. Nearly half (48%) of study participants did not receive all three in-person sessions during their hospitalization. Among enrolled participants, rates of engagement with the smartphone-based assessment and EMI prompts were 51.47%. Regarding acceptability, quantitative and qualitative data supported the perceived acceptability of the intervention, and provided recommendations for future iterations. Well-powered effectiveness (and effectiveness-implementation) studies are needed to determine the effects of this promising and highly scalable intervention approach.
众所周知,住院精神科治疗后的几周是自杀风险最高的时期。需要采取与自杀念头的动态性质相匹配且在这一高风险时期易于实施的干预措施。我们试图确定一项新型注册临床试验的可行性和可接受性,该试验结合了三次简短的面对面治疗课程,在住院期间教授核心认知行为疗法(CBT)技能,随后采用基于智能手机的生态瞬时干预(EMI),以促进出院后28天内情绪管理技能的实时练习。这项试点研究(n = 26)的结果支持了可行性和可接受性的某些方面。关于可行性,所有筛查的住院患者中有14.7%符合研究资格标准。那些不符合资格的患者中有一半(50.3%)是因为他们不属于该治疗所针对的人群(例如,精神病等症状使他们不符合当前研究的资格)。那些基于症状原本符合资格的患者主要因住院时间过短而不符合资格。近一半(48%)的研究参与者在住院期间没有接受全部三次面对面治疗课程。在登记的参与者中,参与基于智能手机的评估和EMI提示的比例为51.47%。关于可接受性,定量和定性数据支持了该干预措施的感知可接受性,并为未来的迭代提供了建议。需要进行有充分效力的有效性(以及有效性-实施)研究,以确定这种有前景且具有高度可扩展性的干预方法的效果。