Touska Philip, Connor Steve E J
Department of Radiology, Guy's and St. Thomas' NHS Foundation Trust, Guy's Hospital, Great Maze Pond, London, SE1 9RT, United Kingdom.
Department of Neuroradiology, Kings College Hospital NHS Trust, Denmark Hill, London, SE5 9RS, United Kingdom.
Eur Radiol. 2025 Apr;35(4):2053-2064. doi: 10.1007/s00330-024-11021-x. Epub 2024 Aug 26.
Although non-malignant, middle ear cholesteatoma can result in significant complications due to local bone erosion and infection. The treatment of cholesteatoma is surgical, but residual disease is common and may be clinically occult, particularly when the canal wall is preserved or reconstructive techniques are employed. Imaging plays a pivotal role in the management of patients with middle ear cholesteatoma-aiding clinical diagnosis, identifying complications, planning surgery, and detecting residual disease at follow-up. Computed tomography is the primary imaging tool in the preoperative setting since it can provide both a surgical roadmap and detect erosive complications of cholesteatoma. The ability of magnetic resonance imaging with non-echoplanar diffusion-weighted sequences to accurately detect residual disease has led to a shift in the diagnostic paradigm for post-surgical follow-up of cholesteatoma, such that routine "second-look" surgery is no longer required. The following practice recommendations are aimed at helping the radiologist choose appropriate imaging approaches and understand the key diagnostic considerations for the evaluation of pre- and post-surgical middle ear cholesteatoma. KEY POINTS: In the preoperative setting, CT is the first-line imaging modality and MRI is reserved for rare clinical scenarios (low evidence). Non-echoplanar imaging (EPI) DWI is the optimal MRI sequence for the detection of residual cholesteatoma (moderate evidence). Non-EPI DWI plays an important role in the postoperative surveillance of cholesteatoma (moderate evidence).
尽管中耳胆脂瘤并非恶性,但由于局部骨质侵蚀和感染,可导致严重并发症。胆脂瘤的治疗方法是手术,但残留病变很常见,且可能在临床上隐匿,尤其是在保留外耳道壁或采用重建技术时。影像学在中耳胆脂瘤患者的管理中起着关键作用——有助于临床诊断、识别并发症、规划手术以及在随访时检测残留病变。计算机断层扫描是术前的主要影像学工具,因为它既能提供手术路线图,又能检测胆脂瘤的侵蚀性并发症。具有非回波平面扩散加权序列的磁共振成像准确检测残留病变的能力,导致了胆脂瘤术后随访诊断模式的转变,以至于不再需要常规的“二次探查”手术。以下实践建议旨在帮助放射科医生选择合适的影像学方法,并了解评估手术前后中耳胆脂瘤的关键诊断要点。要点:在术前,CT是一线影像学检查方式,MRI仅用于罕见临床情况(证据等级低)。非回波平面成像(EPI)DWI是检测残留胆脂瘤的最佳MRI序列(证据等级中等)。非EPI DWI在胆脂瘤术后监测中起重要作用(证据等级中等)。