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75岁以上患者腰椎融合术后持续性下腰痛的预测因素:至少2年随访分析

Predictors of Postoperative Persistent Low Back Pain Following Lumbar Fusion in Patients Older than 75 Years: An Analysis of a Minimum 2-Year Follow-Up.

作者信息

Suzuki Hisataka, Tsujimoto Takeru, Kanayama Masahiro, Oha Fumihiro, Shimamura Yukitoshi, Tanaka Masaru, Hasegawa Yuichi, Fukada Shotaro, Hashimoto Tomoyuki, Iwasaki Norimasa

机构信息

Spine Center, Hakodate Central General Hospital, Hakodate, Hokkaido, Japan.

Spine Center, Hakodate Central General Hospital, Hakodate, Hokkaido, Japan.

出版信息

World Neurosurg. 2024 Nov;191:e256-e264. doi: 10.1016/j.wneu.2024.08.102. Epub 2024 Aug 24.

Abstract

OBJECTIVE

This study aimed to evaluate preoperative and perioperative predictors associated with persistent low back pain (LBP) following lumbar fusion in patients aged >75 years.

METHODS

This single-center retrospective study examined 310 patients aged >75 years who underwent lumbar fusion for lumbar degenerative disease (104 males, 206 females; mean age, 79 [75-90] years). The visual analog scale (VAS) score for LBP was examined preoperatively and 2-year postoperatively. The persistent LBP group comprised patients with a 2-year postoperative LBP-VAS score ≥3. The demographic and preoperative radiographic parameters were also reviewed. A multivariate stepwise logistic regression analysis was performed of variables with values of P < 0.2 on the univariate analysis.

RESULTS

Ninety-nine patients (32%) experienced persistent postoperative LBP. Multivariate logistic regression analysis revealed that age <82 years, history of previous lumbar decompression, and greater preoperative VAS score for LBP were associated with greater postoperative persistent LBP after lumbar fusion, whereas other factors, such as gender, body mass index, osteoporosis, diabetes mellitus, depression, symptom duration, operative time, estimated blood loss, and spinopelvic sagittal parameters, were not.

CONCLUSIONS

This study showed that a relatively younger age, history of preoperative lumbar decompression, and greater preoperative VAS score for LBP were preoperative predictors of postoperative persistent LBP following lumbar fusion in elderly patients. In contrast, preoperative spinopelvic sagittal parameters were not associated with persistent postoperative LBP. Although lumbar fusion is expected to improve LBP, surgeons should pay attention to age, surgical history, and preoperative back pain intensity.

摘要

目的

本研究旨在评估年龄>75岁的患者腰椎融合术后持续性下腰痛(LBP)的术前及围手术期预测因素。

方法

这项单中心回顾性研究纳入了310例年龄>75岁、因腰椎退行性疾病接受腰椎融合术的患者(男性104例,女性206例;平均年龄79[75 - 90]岁)。术前及术后2年检查LBP的视觉模拟量表(VAS)评分。持续性LBP组包括术后2年LBP - VAS评分≥3的患者。还回顾了人口统计学和术前影像学参数。对单因素分析中P<0.2的变量进行多因素逐步逻辑回归分析。

结果

99例患者(32%)术后出现持续性LBP。多因素逻辑回归分析显示,年龄<82岁、既往腰椎减压史以及术前LBP的VAS评分较高与腰椎融合术后持续性LBP的发生相关,而其他因素,如性别、体重指数、骨质疏松症、糖尿病、抑郁症、症状持续时间、手术时间、估计失血量和脊柱骨盆矢状面参数则无关。

结论

本研究表明,相对年轻的年龄、术前腰椎减压史以及术前较高的LBP - VAS评分是老年患者腰椎融合术后持续性LBP的术前预测因素。相比之下,术前脊柱骨盆矢状面参数与术后持续性LBP无关。尽管预期腰椎融合术可改善LBP,但外科医生应关注年龄、手术史和术前背痛强度。

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