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所有原发性大网膜梗死均为真正的特发性吗?五例病例报告。

Are all primary omental infarcts truly idiopathic? Five case reports.

作者信息

Kar Haldun, Khabbazazar Danial, Acar Nihan, Karasu Şebnem, Bağ Halis, Cengiz Fevzi, Dilek Osman Nuri

机构信息

Department of General Surgery, Katip Celebi University Ataturk Training and Research Hospital, İzmir 35150, Türkiye.

Department of Radiology, İzmir Katip Celebi University, School of Medicine, İzmir 35150, Türkiye.

出版信息

World J Clin Cases. 2024 Aug 26;12(24):5596-5603. doi: 10.12998/wjcc.v12.i24.5596.

Abstract

BACKGROUND

Idiopathic omental infarction (IOI) is challenging to diagnose due to its low incidence and vague symptoms. Its differential diagnosis also poses difficulties because it can mimic many intra-abdominal organ pathologies. Although hypercoagulability and thrombosis are among the causes of omental infarction, venous thromboembolism scanning is rarely performed as an etiological investigation.

CASE SUMMARY

The medical records of the 5 cases, who had the diagnosis of IOI by computed tomography, were examined. The majority of the patients were male ( = 4, 80%) and the mean age was 31 years (range: 21-38). The patients had no previous abdominal surgery or a history of any chronic disease. The main complaint of all patients was persistent abdominal pain. Omental infarction was detected in all patients with contrast-enhanced computed tomography. Conservative treatment was initially preferred in all patients, but it failed in 1 patient (20%). After discharge, all patients were referred to the hematology department for thrombophilia screening. Only 1 patient applied for thrombophilia screening and was homozygous for methylenetetrahydrofolate reductase (A1298C mutation) and heterozygous for a factor V Leiden mutation.

CONCLUSION

IOI should be considered in the differential diagnosis in patients presenting with progressive and/or persistent right side abdominal pain. Investigating risk factors such as hypercoagulability in patients with IOI is also important in preventing future conditions related to venous thromboembolism.

摘要

背景

特发性大网膜梗死(IOI)由于发病率低且症状模糊,诊断具有挑战性。其鉴别诊断也存在困难,因为它可模仿许多腹腔内器官病变。尽管高凝状态和血栓形成是大网膜梗死的病因之一,但静脉血栓栓塞扫描作为病因学检查很少进行。

病例总结

检查了5例经计算机断层扫描诊断为IOI的患者的病历。大多数患者为男性(n = 4,80%),平均年龄为31岁(范围:21 - 38岁)。患者既往无腹部手术史或任何慢性疾病史。所有患者的主要主诉均为持续性腹痛。所有患者经增强计算机断层扫描均检测出大网膜梗死。所有患者最初均首选保守治疗,但1例患者(20%)治疗失败。出院后,所有患者均被转诊至血液科进行血栓形成倾向筛查。仅1例患者进行了血栓形成倾向筛查,该患者亚甲基四氢叶酸还原酶为纯合子(A1298C突变),凝血因子V莱顿突变杂合子。

结论

对于出现进行性和/或持续性右侧腹痛的患者,鉴别诊断时应考虑IOI。对IOI患者调查高凝状态等危险因素对于预防未来与静脉血栓栓塞相关的疾病也很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fa0/11269986/6c882eec76a4/WJCC-12-5596-g001.jpg

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