慢性丙型肝炎病毒的肝外表现：文献综述
Extrahepatic Manifestations of Chronic Hepatitis C Virus: Review of the Literature.
作者信息
Stoenescu Andreea Florentina, Florescu Simin Aysel, Popescu Corneliu, Lazar Stefan, Vancea Geta, Ceausu Emanoil, Calistru Petre
机构信息
"Dr. Victor Babes" Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania.
"Carol Davilla" University of Medicine and Pharmacy, Bucharest, Romania.
出版信息
Maedica (Bucur). 2024 Jun;19(2):365-372. doi: 10.26574/maedica.2024.19.2.365.
Abstract
Hepatitis C virus (HCV) affects other tissues besides the liver tissue, with the appearance of extrahepatic manifestations such as cryoglobulinemia, lymphoproliferative diseases, metabolic disorders, neuropsychiatric disorders and others. At the basis of their appearance are immune-mediated mechanisms stimulated by the HCV. The antiviral therapy with direct action initiated in all patients with chronic HCV infection acts on these manifestations, contributing to improving the quality of life, but also to eliminating a public health problem.
摘要
丙型肝炎病毒（HCV）除了影响肝脏组织外，还会影响其他组织，出现诸如冷球蛋白血症、淋巴增生性疾病、代谢紊乱、神经精神障碍等肝外表现。这些表现的出现基于HCV刺激的免疫介导机制。对所有慢性HCV感染患者启动的直接作用抗病毒治疗作用于这些表现，有助于提高生活质量，同时也有助于消除一个公共卫生问题。
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