Department of Otolaryngology-Head & Neck Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Department of Head and Neck Surgery, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Otolaryngol Head Neck Surg. 2024 Dec;171(6):1780-1791. doi: 10.1002/ohn.952. Epub 2024 Aug 27.
To examine prevalence of partial and complete HPV vaccination among middle-aged adults and factors associated with vaccination status.
Nationally representative cross-sectional survey.
United States.
Cohort includes adults aged 30 to 44 years from 2018 to 2022 Behavioral Risk Factor Surveillance System (BRFSS) survey who completed questions about HPV vaccination status. Survey-weighted multivariable logistic regression was utilized to explore factors associated with partial and complete HPV vaccination status.
In this nationally representative cohort of 26,470 US middle-aged adults, 15.8% [95% confidence interval [CI]: 15.1%-16.6%] reported any HPV vaccination, and 6.5% [95% CI: 6.0%-7.0%] reported complete HPV vaccination. On multivariable regression, younger age, female sex, residence in the West or Northeast, higher educational attainment, unmarried status, having a personal healthcare provider, and gay or lesbian sexual orientation were associated with increased likelihood of vaccination. Race was variably associated with vaccination status. Annual income, insurance status, cancer history, head and neck cancer history, and time of last physician checkup were not associated with HPV vaccination status.
HPV vaccination among middle-aged adults who were not previously vaccinated should be based on risk for new HPV infection and possible benefits of vaccination. While our analysis shows that consideration of personal factors likely plays a role in HPV vaccination in this cohort, we also find that gaps in vaccination may exist due to other socioeconomic disparities between sexes, educational attainment levels, racial/ethnic groups, geographic regions, and access to a personal healthcare provider. These factors' influence suggests potential room for improved public health measures.
调查中年人群中 HPV 部分和完全疫苗接种的流行率，并分析与疫苗接种状况相关的因素。
全国代表性的横断面调查。
美国。
该队列纳入了 2018 年至 2022 年期间来自行为风险因素监测系统（BRFSS）调查的年龄在 30 至 44 岁的成年人，他们完成了关于 HPV 疫苗接种状况的问题。利用调查加权多变量逻辑回归分析来探讨与部分和完全 HPV 疫苗接种状况相关的因素。
在这个具有全国代表性的 26470 名美国中年成年人队列中，15.8%（95%置信区间[CI]：15.1%-16.6%）报告了任何 HPV 疫苗接种，6.5%（95%CI：6.0%-7.0%）报告了完全 HPV 疫苗接种。多变量回归分析显示，年龄较小、女性、居住在西部或东北部、受教育程度较高、未婚、有私人医疗保健提供者、同性恋或双性恋性取向与接种疫苗的可能性增加相关。种族与疫苗接种状况存在差异。年收入、保险状况、癌症史、头颈部癌症史和上次医生检查时间与 HPV 疫苗接种状况无关。
对于从未接种过 HPV 疫苗的中年成年人，应根据新的 HPV 感染风险和疫苗接种的潜在益处来决定是否接种。虽然我们的分析表明，在这个队列中，个人因素的考虑可能在 HPV 疫苗接种中发挥作用，但我们也发现，由于性别、教育程度、种族/民族群体、地理位置和获得私人医疗保健提供者之间的其他社会经济差异，可能存在疫苗接种差距。这些因素的影响表明，需要改善公共卫生措施。
