Department of Pathology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Shanghai Jiao Tong University School of Medicine, Shanghai, China.
J Cell Mol Med. 2024 Aug;28(16):e18562. doi: 10.1111/jcmm.18562.
Tumour deposits (TDs) significantly impact colorectal cancer (CRC) prognosis. Integrating TDs into the TNM staging system can enhance individualized disease management. Keeping abreast of evolving TDs research is pivotal for clinical advancement. We comprehensively reviewed both recent and popular literature to grasp the field's essence. Subsequently, a data retrieval sourced articles on TDs in CRC for bibliometric analysis, spanning from 1 January 1935 to 30 April 2023. Bibliometrix software facilitated paper analysis and visualization. Bibliometric indicators, the trends and hotspots were determined. A total of 2147 articles were successfully retrieved. Brown G emerged as the most productive author, and the USA as the most prolific country. Central South University and Memorial Sloan Kettering Cancer Center led productivity. Bradford's law categorized 48 journals into zone 1. Keywords co-occurrence analysis identified three main clusters: the application of TDs in TNM staging, the pathogenesis of TDs, and the assessment of TDs. The trend topic analysis highlighted research focused on refining TDs incorporation into tumour staging. TDs wield enduring medical significance, shaping ongoing research. Much literature focused on confirming TD's prognostic value and optimizing TNM integration. Additionally, it is worth highlighting that TD's enigmatic pathogenesis demands research priority, as it holds the potential to unveil concealed knowledge regarding their development.
肿瘤沉积（TDs）对结直肠癌（CRC）的预后有重要影响。将 TDs 纳入 TNM 分期系统可以增强个体化疾病管理。紧跟 TDs 研究的发展对于临床进展至关重要。我们全面回顾了近期和流行的文献，以掌握该领域的本质。随后，我们从 1935 年 1 月 1 日至 2023 年 4 月 30 日，检索了关于 CRC 中 TDs 的文献进行了文献计量学分析。我们使用 Bibliometrix 软件进行了论文分析和可视化。确定了文献计量指标、趋势和热点。共成功检索到 2147 篇文章。Brown G 是最有成果的作者，美国是最有成果的国家。中南大学和纪念斯隆凯特琳癌症中心在生产力方面处于领先地位。布拉德福定律将 48 种期刊分为 1 区。关键词共现分析确定了三个主要聚类：TDs 在 TNM 分期中的应用、TDs 的发病机制以及 TDs 的评估。趋势主题分析强调了专注于完善 TDs 纳入肿瘤分期的研究。TDs 具有持久的医学意义，塑造着正在进行的研究。许多文献集中在确认 TD 的预后价值和优化 TNM 整合上。此外，值得强调的是，TD 神秘的发病机制需要优先研究，因为它有可能揭示关于其发展的隐藏知识。
