Ratnasamy Philip P, Gouzoulis Michael J, Jabbouri Sahir S, Rubio Daniel R, Grauer Jonathan N
Department of Orthopedics and Rehabilitation, Yale School of Medicine, New Haven, CT.
Spine (Phila Pa 1976). 2025 Jul 1;50(13):E242-E247. doi: 10.1097/BRS.0000000000005130. Epub 2024 Aug 27.
Retrospective cohort study.
To assess relative odds of perioperative complications, readmissions, and 5-year survival to reoperation for patients undergoing 3-level lumbar decompression who undergo 3-level fusion relative to 1-level fusion.
Patients undergoing multilevel lumbar decompression may be indicated for fusion at one or more levels. The question of fusing only one level with indications such as spondylolisthesis or fusing all levels decompressed is of clinical interest in both the short and longer term.
Patients undergoing 3-level lumbar decompression were extracted from the PearlDiver M165Orto database. The subset of these patients undergoing concomitant 3-level and 1-level lumbar fusion were identified and matched 1:1 based on patient age, sex, and Elixhauser Comorbidity Index scores. The incidence and odds of 90-day postoperative adverse events were compared between the two groups by multivariable analysis, and a comparative 5-year survival to lumbar spinal reoperation was determined.
After matching, 28,276 patients were identified as undergoing 3-level lumbar decompression with 3-level fusion and the same for those undergoing 3-level decompression with 1-level fusion. Controlling for patient age, sex, and Elixhauser Comorbidity Index, patients undergoing 3-level fusion had significantly greater odds ratio (OR) of many 90-day adverse events and aggregated any (OR: 1.42), serious (OR: 1.44), and minor (OR: 1.42) adverse events, as well as readmissions (OR: 1.51; P < 0.0001 for all). Five-year survival to reoperation was significantly lower for those undergoing 3-level decompression with 3-level fusion ( P < 0.0001).
Patients undergoing 3-level lumbar decompression who underwent 3-level fusion were found to be at significantly greater odds of 90-day postoperative adverse events, readmissions, and 5-year reoperations relative to those undergoing 1-level fusion. The current data support the concept of limiting fusion to the levels with specific indications in the setting of multilevel lumbar decompressions and not needing to match the decompression and fusion levels.
回顾性队列研究。
评估接受三级腰椎减压并进行三级融合的患者与接受一级融合的患者相比,围手术期并发症、再入院率及再次手术5年生存率的相对比值。
接受多级腰椎减压的患者可能需要在一个或多个节段进行融合。仅融合一个节段(如腰椎滑脱等情况)还是融合所有减压节段,无论短期还是长期,都是临床关注的问题。
从PearlDiver M165Orto数据库中提取接受三级腰椎减压的患者。确定这些患者中同时接受三级和一级腰椎融合的亚组,并根据患者年龄、性别和埃利克斯豪泽合并症指数评分进行1:1匹配。通过多变量分析比较两组术后90天不良事件的发生率和比值,并确定腰椎再次手术的5年生存率比较情况。
匹配后,28276例患者被确定为接受三级腰椎减压并进行三级融合,同样数量的患者接受三级减压并进行一级融合。在控制患者年龄、性别和埃利克斯豪泽合并症指数后,接受三级融合的患者发生多种90天不良事件以及汇总的任何(比值比:1.42)、严重(比值比:1.44)和轻微(比值比:1.42)不良事件以及再入院(比值比:1.51;所有P<0.0001)的比值比显著更高。接受三级减压并进行三级融合的患者再次手术的5年生存率显著更低(P<0.0001)。
与接受一级融合的患者相比,接受三级腰椎减压并进行三级融合的患者术后90天不良事件、再入院率及5年再次手术的几率显著更高。目前的数据支持在多级腰椎减压情况下将融合限制在有特定指征的节段,而无需使减压节段与融合节段匹配的概念。