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与碳水化合物代谢相关的脂质代谢

Lipid Metabolism in Relation to Carbohydrate Metabolism.

作者信息

Akiki Perla, Delamotte Pierre, Montagne Jacques

机构信息

Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.

出版信息

Adv Exp Med Biol. 2024 Aug 28. doi: 10.1007/5584_2024_821.

Abstract

Carbohydrates and lipids integrate into a complex metabolic network that is essential to maintain homeostasis. In insects, as in most metazoans, dietary carbohydrates are taken up as monosaccharides whose excess is toxic, even at relatively low concentrations. To cope with this toxicity, monosaccharides are stored either as glycogen or neutral lipids, the latter constituting a quasi-unlimited energy store. Breakdown of these stores in response to energy demand depends on insect species and on several physiological parameters. In this chapter, we review the multiple metabolic pathways and strategies linking carbohydrates and lipids that insects utilize to respond to nutrient availability, food scarcity or physiological activities.

摘要

碳水化合物和脂质整合到一个复杂的代谢网络中,这对于维持体内平衡至关重要。在昆虫中,如同大多数后生动物一样,膳食碳水化合物以单糖形式被摄取,即使在相对较低的浓度下,其过量也是有毒的。为了应对这种毒性,单糖要么以糖原形式储存,要么以中性脂质形式储存,后者构成了一种几乎无限的能量储备。根据能量需求分解这些储备取决于昆虫种类和几个生理参数。在本章中,我们综述了昆虫用来应对营养物质供应、食物短缺或生理活动的多种连接碳水化合物和脂质的代谢途径和策略。

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