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Editorial: Epilepsy and Alzheimer's disease: shared pathology, clinical presentations, and targets for treatment.社论:癫痫与阿尔茨海默病:共同的病理学、临床表现及治疗靶点
Front Neurol. 2024 Aug 13;15:1441996. doi: 10.3389/fneur.2024.1441996. eCollection 2024.
2
CSF tau and the CSF tau/ABeta ratio for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI).脑脊液tau蛋白及脑脊液tau蛋白与β淀粉样蛋白比值在轻度认知障碍(MCI)患者中用于诊断阿尔茨海默病性痴呆及其他痴呆。
Cochrane Database Syst Rev. 2017 Mar 22;3(3):CD010803. doi: 10.1002/14651858.CD010803.pub2.
3
Joint spatial associations of amyloid beta and tau pathology in Down syndrome and preclinical Alzheimer's disease: Cross-sectional associations with early cognitive impairments.唐氏综合征和临床前阿尔茨海默病中β-淀粉样蛋白和tau病理的联合空间关联:与早期认知障碍的横断面关联
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The association of seizure control with neuropathology in dementia.痴呆症中癫痫控制与神经病理学的关联。
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A cross-sectional study of α-synuclein seed amplification assay in Alzheimer's disease neuroimaging initiative: Prevalence and associations with Alzheimer's disease biomarkers and cognitive function.阿尔茨海默病神经影像学倡议中α-突触核蛋白种子扩增测定的横断面研究:患病率及与阿尔茨海默病生物标志物和认知功能的相关性。
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Alzheimers Dement. 2025 Feb;21(2):e14458. doi: 10.1002/alz.14458. Epub 2024 Dec 23.

本文引用的文献

1
Persistent ∆FosB expression limits recurrent seizure activity and provides neuroprotection in the dentate gyrus of APP mice.持久的 ∆FosB 表达限制了 APP 小鼠齿状回的复发性癫痫活动并提供了神经保护。
Prog Neurobiol. 2024 Jun;237:102612. doi: 10.1016/j.pneurobio.2024.102612. Epub 2024 Apr 19.
2
The crosstalk between epilepsy and dementia: A systematic review and meta-analysis.癫痫与痴呆的相互作用:系统评价和荟萃分析。
Epilepsy Behav. 2024 Mar;152:109640. doi: 10.1016/j.yebeh.2024.109640. Epub 2024 Jan 31.
3
Similar brain proteomic signatures in Alzheimer's disease and epilepsy.阿尔茨海默病和癫痫的相似脑部蛋白质组学特征。
Acta Neuropathol. 2024 Jan 30;147(1):27. doi: 10.1007/s00401-024-02683-4.
4
CSF biomarkers in patients with epilepsy in Alzheimer's disease: a nation-wide study.阿尔茨海默病合并癫痫患者的脑脊液生物标志物:一项全国性研究。
Brain Commun. 2022 Aug 17;4(4):fcac210. doi: 10.1093/braincomms/fcac210. eCollection 2022.
5
Sleep: The Tip of the Iceberg in the Bidirectional Link Between Alzheimer's Disease and Epilepsy.睡眠:阿尔茨海默病与癫痫双向联系中的冰山一角。
Front Neurol. 2022 Apr 11;13:836292. doi: 10.3389/fneur.2022.836292. eCollection 2022.
6
The Significance of Subclinical Epileptiform Activity in Alzheimer's Disease: A Review.阿尔茨海默病中亚临床癫痫样活动的意义:综述
Front Neurol. 2022 Apr 4;13:856500. doi: 10.3389/fneur.2022.856500. eCollection 2022.
7
Effect of Levetiracetam on Cognition in Patients With Alzheimer Disease With and Without Epileptiform Activity: A Randomized Clinical Trial.左乙拉西坦对伴有和不伴有痫样活动的阿尔茨海默病患者认知功能的影响:一项随机临床试验。
JAMA Neurol. 2021 Nov 1;78(11):1345-1354. doi: 10.1001/jamaneurol.2021.3310.
8
Bi-directional association between epilepsy and dementia: The Framingham Heart Study.癫痫与痴呆的双向关联:弗雷明汉心脏研究。
Neurology. 2020 Dec 15;95(24):e3241-e3247. doi: 10.1212/WNL.0000000000011077. Epub 2020 Oct 23.
9
Genes Bound by ΔFosB in Different Conditions With Recurrent Seizures Regulate Similar Neuronal Functions.在复发性癫痫的不同条件下与ΔFosB结合的基因调控相似的神经元功能。
Front Neurosci. 2020 May 28;14:472. doi: 10.3389/fnins.2020.00472. eCollection 2020.
10
Effect of donepezil and memantine on improvement of cognitive function in patients with temporal lobe epilepsy.多奈哌齐和美金刚对颞叶癫痫患者认知功能改善的影响。
J Res Med Sci. 2020 Mar 18;25:29. doi: 10.4103/jrms.JRMS_209_19. eCollection 2020.

Editorial: Epilepsy and Alzheimer's disease: shared pathology, clinical presentations, and targets for treatment.

作者信息

Leeman-Markowski Beth, Chin Jeannie, Leitner Dominique, Vossel Keith

机构信息

Neurology Service, VA New York Harbor Healthcare System, New York, NY, United States.

Department of Neurology, Comprehensive Epilepsy Center, New York University Langone Health, New York, NY, United States.

出版信息

Front Neurol. 2024 Aug 13;15:1441996. doi: 10.3389/fneur.2024.1441996. eCollection 2024.

DOI:10.3389/fneur.2024.1441996
PMID:39193148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11348586/
Abstract
摘要