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跨膜9超家族成员1作为尿路上皮癌生物标志物的潜在作用。

Potential role of transmembrane 9 superfamily member 1 as a biomarker in urothelial cancer.

作者信息

Pinto Alvaro, Ocanto Abrahams, Couñago Felipe

机构信息

Department of Medical Oncology, University Hospital La Paz, Paseo Castellana 261, Madrid 28046, Spain.

Department of Radiation Oncology, GenesisCare, Hospital Universitario San Francisco de Asís, Madrid 28002, Spain.

出版信息

World J Clin Oncol. 2024 Aug 24;15(8):965-967. doi: 10.5306/wjco.v15.i8.965.

Abstract

Bladder cancer is a urological tumor with high rates of recurrence despite recent advances in novel therapies. Many proteins involved in the molecular mechanisms are currently an enigma, especially the transmembrane 9 superfamily member 1 which has an unclear function. Wei published the function and mechanism of this protein, and showed that it could participate in the proliferation, migration and invasion of tumor cells in bladder cancer, therefore treatments directed against this protein may be beneficial in avoiding this condition.

摘要

膀胱癌是一种泌尿系统肿瘤,尽管新型疗法取得了最新进展,但复发率仍然很高。许多参与分子机制的蛋白质目前仍是个谜,尤其是功能尚不清楚的跨膜9超家族成员1。Wei发表了这种蛋白质的功能和机制,并表明它可能参与膀胱癌肿瘤细胞的增殖、迁移和侵袭,因此针对这种蛋白质的治疗可能有助于避免这种疾病。

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本文引用的文献

1
TM9SF1 promotes bladder cancer cell growth and infiltration.
World J Clin Oncol. 2024 Feb 24;15(2):302-316. doi: 10.5306/wjco.v15.i2.302.
3
A Prognostic Model Based on mRNA Expression Analysis of Esophageal Squamous Cell Carcinoma.
Front Bioeng Biotechnol. 2022 Mar 1;10:823619. doi: 10.3389/fbioe.2022.823619. eCollection 2022.
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Identification of common differentially expressed genes in urinary bladder cancer.
PLoS One. 2011 Apr 4;6(4):e18135. doi: 10.1371/journal.pone.0018135.

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