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本文引用的文献

1
TM9SF1 promotes bladder cancer cell growth and infiltration.跨膜9超家族成员1（TM9SF1）促进膀胱癌细胞的生长和浸润。
World J Clin Oncol. 2024 Feb 24;15(2):302-316. doi: 10.5306/wjco.v15.i2.302.
2
mAm methyltransferase PCIF1 is essential for aggressiveness of gastric cancer cells by inhibiting TM9SF1 mRNA translation.mAm甲基转移酶PCIF1通过抑制TM9SF1 mRNA翻译对胃癌细胞的侵袭性至关重要。
Cell Discov. 2022 May 21;8(1):48. doi: 10.1038/s41421-022-00395-1.
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A Prognostic Model Based on mRNA Expression Analysis of Esophageal Squamous Cell Carcinoma.基于食管鳞状细胞癌mRNA表达分析的预后模型
Front Bioeng Biotechnol. 2022 Mar 1;10:823619. doi: 10.3389/fbioe.2022.823619. eCollection 2022.
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Identification of an autophagy-related gene signature for survival prediction in patients with cervical cancer.鉴定与自噬相关的基因特征，用于预测宫颈癌患者的生存情况。
J Ovarian Res. 2020 Nov 7;13(1):131. doi: 10.1186/s13048-020-00730-8.
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Identification of common differentially expressed genes in urinary bladder cancer.鉴定膀胱癌中的常见差异表达基因。
PLoS One. 2011 Apr 4;6(4):e18135. doi: 10.1371/journal.pone.0018135.
6
A consensus definition of patients with metastatic urothelial carcinoma who are unfit for cisplatin-based chemotherapy.不适合基于顺铂化疗的转移性尿路上皮癌患者的共识定义。
Lancet Oncol. 2011 Mar;12(3):211-4. doi: 10.1016/S1470-2045(10)70275-8.
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High-throughput functional screening for autophagy-related genes and identification of TM9SF1 as an autophagosome-inducing gene.自噬相关基因的高通量功能筛选及TM9SF1作为自噬体诱导基因的鉴定。
Autophagy. 2009 Jan;5(1):52-60. doi: 10.4161/auto.5.1.7247. Epub 2009 Jan 23.
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Neoadjuvant chemotherapy in invasive bladder cancer: update of a systematic review and meta-analysis of individual patient data advanced bladder cancer (ABC) meta-analysis collaboration.浸润性膀胱癌的新辅助化疗：晚期膀胱癌（ABC）荟萃分析协作组对个体患者数据的系统评价和荟萃分析更新
Eur Urol. 2005 Aug;48(2):202-5; discussion 205-6. doi: 10.1016/j.eururo.2005.04.006. Epub 2005 Apr 21.

跨膜9超家族成员1作为尿路上皮癌生物标志物的潜在作用。

Potential role of transmembrane 9 superfamily member 1 as a biomarker in urothelial cancer.

作者信息

Pinto Alvaro, Ocanto Abrahams, Couñago Felipe

机构信息

Department of Medical Oncology, University Hospital La Paz, Paseo Castellana 261, Madrid 28046, Spain.

Department of Radiation Oncology, GenesisCare, Hospital Universitario San Francisco de Asís, Madrid 28002, Spain.

出版信息

World J Clin Oncol. 2024 Aug 24;15(8):965-967. doi: 10.5306/wjco.v15.i8.965.

DOI:10.5306/wjco.v15.i8.965
PMID:39193159
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11346073/
Abstract

Bladder cancer is a urological tumor with high rates of recurrence despite recent advances in novel therapies. Many proteins involved in the molecular mechanisms are currently an enigma, especially the transmembrane 9 superfamily member 1 which has an unclear function. Wei published the function and mechanism of this protein, and showed that it could participate in the proliferation, migration and invasion of tumor cells in bladder cancer, therefore treatments directed against this protein may be beneficial in avoiding this condition.

摘要

膀胱癌是一种泌尿系统肿瘤，尽管新型疗法取得了最新进展，但复发率仍然很高。许多参与分子机制的蛋白质目前仍是个谜，尤其是功能尚不清楚的跨膜9超家族成员1。Wei发表了这种蛋白质的功能和机制，并表明它可能参与膀胱癌肿瘤细胞的增殖、迁移和侵袭，因此针对这种蛋白质的治疗可能有助于避免这种疾病。