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结直肠癌手术术后切口感染危险因素的Meta分析

Meta-analysis of postoperative incision infection risk factors in colorectal cancer surgery.

作者信息

Jia Li, Zhao Huacai, Liu Jia

机构信息

Department of Infection Control, People's Hospital of Dayi County, Chengdu, Sichuan Province, China.

Department of Urology, People's Hospital of Dayi County, Chengdu, Sichuan Province, China.

出版信息

Front Surg. 2024 Aug 13;11:1415357. doi: 10.3389/fsurg.2024.1415357. eCollection 2024.

Abstract

OBJECTIVE

To evaluate the risk factors for postoperative incision infection in colorectal cancer, this meta-analysis aimed to identify key variables impacting infection incidence following colorectal cancer surgery.

METHODS

Utilizing a meta-analytical approach, studies published from January 2015 to December 2022 were systematically collected and analyzed through the assessment of factors like body mass index, diabetes, albumin levels, malnutrition, and surgical duration.

RESULTS

The meta-analysis of eleven high-quality studies revealed that elevated BMI, diabetes, low albumin levels, malnutrition, and extended surgical duration were associated with increased infection risk, while laparoscopic procedures showed potential for risk reduction.

CONCLUSIONS

This study underscores the significance of preoperative risk assessment and management in mitigating postoperative incision infections in colorectal cancer patients. The findings present actionable insights for clinicians to enhance patient prognoses and overall quality of life.

摘要

目的

为评估结直肠癌术后切口感染的危险因素,本荟萃分析旨在确定影响结直肠癌手术后感染发生率的关键变量。

方法

采用荟萃分析方法,系统收集2015年1月至2022年12月发表的研究,并通过评估体重指数、糖尿病、白蛋白水平、营养不良和手术时长等因素进行分析。

结果

对11项高质量研究的荟萃分析显示,BMI升高、糖尿病、白蛋白水平低、营养不良和手术时间延长与感染风险增加相关,而腹腔镜手术显示出降低风险的潜力。

结论

本研究强调了术前风险评估和管理对降低结直肠癌患者术后切口感染的重要性。研究结果为临床医生改善患者预后和整体生活质量提供了可操作的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a985/11347452/d30fd5513bae/fsurg-11-1415357-g001.jpg

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