Solanki D L, Blackburn B C
Obstet Gynecol. 1985 Mar;65(3 Suppl):14S-17S.
Thrombocytopenia in four healthy pregnant women proved to be spurious and caused by in vitro clumping of platelets (three) or adherence of platelets to granulocytes (one) in the presence of edetic acid used to anticoagulate the blood. All had normal vaginal deliveries without unusual bleeding. One of the newborns transiently exhibited the phenomenon of platelet clumping in vitro, probably due to transplacental transfer of the platelet agglutinin from the mother. Recognition of these laboratory artifacts is important to avoid unwarranted investigations and inappropriate management of the mother and infant. Careful examination of a blood smear in all thrombocytopenic patients is the best safeguard against being misled by spurious thrombocytopenia.
事实证明，四名健康孕妇的血小板减少是假性的，是由用于血液抗凝的乙二胺四乙酸存在时血小板在体外结块（三例）或血小板黏附于粒细胞（一例）所致。所有孕妇均经阴道正常分娩，无异常出血。其中一名新生儿在体外短暂出现血小板结块现象，可能是由于母亲的血小板凝集素经胎盘转移所致。认识到这些实验室假象对于避免对母婴进行不必要的检查和不恰当的处理很重要。对所有血小板减少患者仔细检查血涂片是防止被假性血小板减少误导的最佳保障。
