Varela Daniel, Sandhu Amneet, Zipse Matthew, Aleong Ryan Gerrard
Cardiology Department, University of Colorado Hospital, Aurora, CO, USA.
Cardiology Department, Rocky Mountain Regional VA Medical Center, Aurora, CO, USA.
J Innov Card Rhythm Manag. 2024 Aug 15;15(8):5985-5989. doi: 10.19102/icrm.2024.15081. eCollection 2024 Aug.
Conduction system pacing (CSP) has emerged as an alternative to cardiac resynchronization therapy (CRT); however, there is limited experience with CSP using implantable cardiac defibrillator (ICD) leads. The achievement of CSP with an ICD lead may yield comparable results to cardiac resynchronization therapy defibrillator (CRT-D) therapy using fewer leads. We implanted the Biotronik Linox DX "VDD"-programmable ICD lead in a swine model to investigate the feasibility of "single-lead" CRT-D implantation. With the lead embedded in the basal right ventricular septum, morphologic criteria for CSP were achieved, and successful defibrillation was performed while maintaining atrial sensing. Future work may assure reproducibility of these findings and further determine the feasibility of a single-lead CRT-D.
传导系统起搏（CSP）已成为心脏再同步治疗（CRT）的一种替代方法；然而，使用植入式心脏除颤器（ICD）导线进行CSP的经验有限。使用ICD导线实现CSP可能会产生与使用较少导线的心脏再同步治疗除颤器（CRT-D）疗法相当的结果。我们在猪模型中植入了百多力Linox DX“VDD”可编程ICD导线，以研究“单导线”CRT-D植入的可行性。将导线嵌入右心室基底部间隔后，达到了CSP的形态学标准，并且在维持心房感知的同时成功进行了除颤。未来的工作可能会确保这些发现的可重复性，并进一步确定单导线CRT-D的可行性。
